Inter-organ crosstalk during development and progression of type 2 diabetes mellitus
G Xourafa, M Korbmacher, M Roden - Nature Reviews Endocrinology, 2024 - nature.com
Type 2 diabetes mellitus (T2DM) is characterized by tissue-specific insulin resistance and
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …
Promise and Perils of MicroRNA Discovery Research: Working Toward Quality Over Quantity
Since the first microRNA (miRNA) was described in 1993 in the humble worm
Caenorhabditis elegans, the miRNA field has boomed, with more than 100 000 related …
Caenorhabditis elegans, the miRNA field has boomed, with more than 100 000 related …
Revolutionary innovations in diabetes research: from biomarkers to genomic medicine
T Addissouky, M Ali… - Iranian journal of …, 2023 - publish.kne-publishing.com
Diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia resulting
from inadequate insulin signaling. Current management relies on biomarkers such as …
from inadequate insulin signaling. Current management relies on biomarkers such as …
Ultrasensitive photoelectrochemical biosensor for dual-miRNAs detection based on molecular logic gates and methylene blue sensitized ZnO@ CdS@ Au nanorods
S Bi, H He, F Gao, Y Zhao - ACS Applied Materials & Interfaces, 2024 - ACS Publications
The occurrence of cancer is often closely related to multiple tumor markers, so it is important
to develop multitarget detection methods. By the proper design of the input signals and …
to develop multitarget detection methods. By the proper design of the input signals and …
Integrated Analysis of lncRNA–miRNA–mRNA Regulatory Network in Rapamycin-Induced Cardioprotection against Ischemia/Reperfusion Injury in Diabetic Rabbits
The inhibition of mammalian target of rapamycin (mTOR) with rapamycin (RAPA) provides
protection against myocardial ischemia/reperfusion (I/R) injury in diabetes. Since …
protection against myocardial ischemia/reperfusion (I/R) injury in diabetes. Since …
Applicability of mesenchymal stem cell-derived exosomes as a cell-free miRNA therapy and epigenetic modifiers for diabetes
S Sharma, R Bhonde - Epigenomics, 2023 - Taylor & Francis
Given that exosome nanovesicles constitute various growth factors, miRNAs and lncRNAs,
they have implications for epigenetic modifications. Few studies have shown that exosomes …
they have implications for epigenetic modifications. Few studies have shown that exosomes …
The Parasite‐Derived Peptide, FhHDM‐1, Selectively Modulates miRNA Expression in β‐Cells to Prevent Apoptotic Pathways Induced by Proinflammatory Cytokines
We have previously identified a parasite‐derived peptide, FhHDM‐1, that prevented the
progression of diabetes in nonobese diabetic (NOD) mice. Disease prevention was …
progression of diabetes in nonobese diabetic (NOD) mice. Disease prevention was …
Exploration of the miR‐187‐3p/CNR2 pathway in modulating osteoblast differentiation and treating postmenopausal osteoporosis through mechanical stress
L Zhang, C Zeng, J Huang, H Yan, Y Jiang… - The FASEB …, 2024 - Wiley Online Library
This study aimed to explore how mechanical stress affects osteogenic differentiation via the
miR‐187‐3p/CNR2 pathway. To conduct this study, 24 female C57BL/6 mice, aged 8 weeks …
miR‐187‐3p/CNR2 pathway. To conduct this study, 24 female C57BL/6 mice, aged 8 weeks …
Lessons and Applications of Omics Research in Diabetes Epidemiology
G Yu, HCH Tam, C Huang, M Shi, CKP Lim… - Current Diabetes …, 2024 - Springer
Abstract Purpose of Review Recent advances in genomic technology and molecular
techniques have greatly facilitated the identification of disease biomarkers, advanced …
techniques have greatly facilitated the identification of disease biomarkers, advanced …
[HTML][HTML] Overexpression of miR-199b-5p in Colony Forming Unit-Hill's Colonies Positively Mediates the Inflammatory Response in Subclinical Cardiovascular Disease …
Well-controlled type 1 diabetes (T1DM) is characterized by inflammation and endothelial
dysfunction, thus constituting a suitable model of subclinical cardiovascular disease (CVD) …
dysfunction, thus constituting a suitable model of subclinical cardiovascular disease (CVD) …