Interactions of platelets with circulating tumor cells contribute to cancer metastasis

S Anvari, E Osei, N Maftoon - Scientific Reports, 2021 - nature.com
Recent studies have suggested that platelets have a crucial role in enhancing the survival of
circulating tumor cells in the bloodstream and aggravating cancer metastasis. The main …

The effect of stiffened diabetic red blood cells on wall shear stress in a reconstructed 3D microaneurysm

B Czaja, J de Bouter, M Heisler… - Computer Methods in …, 2022 - Taylor & Francis
Blood flow within the vasculature of the retina has been found to influence the progression of
diabetic retinopathy. In this research cell resolved blood flow simulations are used to study …

Red blood cell and platelet diffusivity and margination in the presence of cross-stream gradients in blood flows

G Závodszky, B van Rooij, B Czaja, V Azizi… - Physics of …, 2019 - pubs.aip.org
The radial distribution of cells in blood flow inside vessels is highly non-homogeneous. This
leads to numerous important properties of blood, yet the mechanisms sha** these …

Parallel modeling of cell suspension flow in complex micro-networks with inflow/outflow boundary conditions

G Li, T Ye, X Li - Journal of Computational Physics, 2020 - Elsevier
We proposed a parallel framework with inflow/outflow boundary conditions for particle-
based simulations of cell suspension flow through complex micro-networks that is often …

Numerical study of ultra-large von Willebrand factor multimers in coagulopathy

N Rahmati, P Keshavarz Motamed… - … and Modeling in …, 2024 - Springer
An excessive von Willebrand factor (VWF) secretion, coupled with a moderate to severe
deficiency of ADAMTS13 activity, serves as a linking mechanism between inflammation to …

Reconstruction of proper numerical inlet boundary conditions for draft tube flow simulations using machine learning

P Véras, O Métais, G Balarac, D Georges… - Computers & …, 2023 - Elsevier
This paper discusses an innovative strategy to determine appropriate mean and fluctuating
inlet boundary conditions for the numerical flow simulations of a hydraulic turbine draft tube …

Heterogeneous partition of cellular blood-borne nanoparticles through microvascular bifurcations

ZL Liu, JR Clausen, JL Wagner, KS Butler… - Physical Review E, 2020 - APS
Blood flowing through microvascular bifurcations has been an active research topic for many
decades, while the partitioning pattern of nanoscale solutes in the blood remains relatively …

The effects of micro-vessel curvature induced elongational flows on platelet adhesion

CJ Spieker, G Závodszky, C Mouriaux… - Annals of Biomedical …, 2021 - Springer
The emerging profile of blood flow and the cross-sectional distribution of blood cells have far
reaching biological consequences in various diseases and vital internal processes, such as …

Comparison of multiphase SPH and LBM approaches for the simulation of intermittent flows

T Douillet-Grellier, S Leclaire, D Vidal… - Computational particle …, 2019 - Springer
Smoothed particle hydrodynamics (SPH) and lattice Boltzmann method (LBM) are
increasingly popular and attractive methods that propose efficient multiphase formulations …

Cell-resolved blood flow simulations of saccular aneurysms: effects of pulsatility and aspect ratio

B Czaja, G Závodszky… - Journal of The …, 2018 - royalsocietypublishing.org
We study the effect of pulsatile flow on the transport of red blood cells (RBCs) and platelets
into aneurysm geometries with varying dome-to-neck aspect ratios (AR). We use a validated …