Therapeutic mechanisms of psychedelics and entactogens

BD Heifets, DE Olson - Neuropsychopharmacology, 2024 - nature.com
Recent clinical and preclinical evidence suggests that psychedelics and entactogens may
produce both rapid and sustained therapeutic effects across several indications. Currently …

Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics

AM Jaster, J González-Maeso - Molecular psychiatry, 2023 - nature.com
Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

A framework for assessment of adverse events occurring in psychedelic-assisted therapies

R Palitsky, DM Kaplan, J Perna… - Journal of …, 2024 - journals.sagepub.com
Objective: Despite considerable research examining the efficacy of psychedelic-assisted
therapies (PATs) for treating psychiatric disorders, assessment of adverse events (AEs) in …

The psychedelic effects of cannabis: A review of the literature

D Wolinsky, FS Barrett… - Journal of …, 2024 - journals.sagepub.com
Cannabis and classic psychedelics are controlled substances with emerging evidence of
efficacy in the treatment of a variety of psychiatric illnesses. Cannabis has largely not been …

Nature-themed video intervention may improve cardiovascular safety of psilocybin-assisted therapy for alcohol use disorder

KG Heinzerling, K Sergi, M Linton, R Rich… - Frontiers in …, 2023 - frontiersin.org
Introduction Psychedelic-assisted therapy with psilocybin has shown promise in Phase 2
trials for alcohol use disorder (AUD). Set and setting, particularly factors facilitating a …

Disentangling the acute subjective effects of classic psychedelics from their enduring therapeutic properties

MA Atiq, MR Baker, JLV Voort, MV Vargas… - Psychopharmacology, 2024 - Springer
Recent research with classic psychedelics suggests significant therapeutic potential,
particularly for neuropsychiatric disorders. A mediating influence behind symptom resolution …

Biological studies of clavine alkaloids targeting CNS receptors

NR Tasker, EJ Pazur, P Wipf - Frontiers in psychiatry, 2023 - frontiersin.org
In contrast to well established psychedelics such as lysergic acid diethylamide (LSD) and
psilocybin, ergot alkaloids of the clavine subclass have not been thoroughly investigated, in …

[HTML][HTML] 'Mind-Revealing'Psychedelic States: Psychological Processes in Subjective Experiences That Drive Positive Change

RFE Walther, HT van Schie - Psychoactives, 2024 - mdpi.com
This narrative review explores the utilization of psychedelic states in therapeutic contexts,
deliberately shifting the focus from psychedelic substances back to the experiential …

Psychedelics, with a focus on psilocybin: Issues for the clinician

A Garakani, JL Alexander, CR Sumner… - Journal of Psychiatric …, 2023 - journals.lww.com
There has been a burgeoning interest in psychedelics among the public, state legislatures,
psychiatrists and other clinical providers, and within the research community. Increasing …