Importance Osteoarthritis (OA) is the most common joint disease, affecting an estimated
more than 240 million people worldwide, including an estimated more than 32 million in the …

Identification and management of patients at high bleeding risk undergoing percutaneous
coronary intervention are of major importance, but a lack of standardization in defining this …

Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important
cause of peptic ulcer disease and gastric cancer. H. pylorimay also have a role in …

Description Proton pump inhibitors (PPIs) are among the most commonly used medications
in the world. Developed for the treatment and prevention of acid-mediated upper …

Background & Aims The purpose of this review is to evaluate the risks associated with long-
term use of proton pump inhibitors (PPIs), focusing on long-term use of PPIs for three …

Pancreatic cysts are very common with the majority incidentally identified. There are several
types of pancreatic cysts; some types can contain cancer or have malignant potential …

Proton pump inhibitors (PPIs) were clinically introduced more than 25 years ago and have
since proven to be invaluable, safe, and effective agents for the management of a variety of …

Objective To develop an evidence-based guideline to help clinicians make decisions about
when and how to safely taper or stop proton pump inhibitors (PPIs); to focus on the highest …

Abstract The Japanese Society of Gastroenterology (JSGE) revised the third edition of
evidence-based clinical practice guidelines for peptic ulcer disease in 2020 and created an …

Peptic ulcer disease had a tremendous effect on morbidity and mortality until the last
decades of the 20th century, when epidemiological trends started to point to an impressive …