Antimicrobial resistance is widely recognized as a grave threat to global health in the 21st
century, since the past decades have seen a dramatic increase in human-pathogenic …

The chemistry of diazo compounds has a long history. It has attracted attention because of
their various useful applications in organic synthesis. In particular, they have been used …

2-Azetidinone, a β-lactam four member heterocyclic compound involved in research aimed
to evaluate new products that possess interesting biological activities. These compounds …

Synthesis of novel 1, 2, 3-triazole-linked β-lactam–bile acid conjugates 17–24 using 1, 3-
dipolar cycloaddition reaction of azido β-lactam and terminal alkyne of bile acids in the …

Due to the widespread emergence of resistant bacterial strains, an urgent need for the
development of new antibacterial agents with novel modes of action has emerged. The …

Abstract Azetidin-2-ones, commonly referred as β-lactams, represent a unique ring system,
with interesting chemistry and great biological potential. Besides its well known antibiotic …

The development of new antibiotics with low environmental persistence is of utmost
importance in contrasting phenomena of antibiotic resistance. In this study, the persistence …

Background: Since its landmark discovery in 1928, penicillin has had a profound impact on
the quality of human life. The ability to treat and cure deadly infections and bacterial …

The azetidinone core-structure offers a unique approach to the design and synthesis of new
derivatives with unique biological properties. During the last two decades researches …

In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio
morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and …