The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early
repolarization syndrome (ERS), have captured the interest of the cardiology community over …

Evidence from human genetic pain disorders shows that voltage-gated sodium channel α-
subtypes Nav1. 7, Nav1. 8 and Nav1. 9 are important in the peripheral signalling of pain …

Sudden cardiac death occurs in a broad spectrum of cardiac pathologies and is an important
cause of mortality in the general population. Genetic studies conducted during the past 20 …

Brugada syndrome (BrS) is an “inherited” condition characterized by predisposition to
syncope and cardiac arrest, predominantly during sleep. The prevalence is∼ 1: 2,000, and …

Brugada syndrome (BrS) was first described as a primary electrical disorder predisposing to
the risk of sudden cardiac death and characterized by right precordial lead ST elevation …

Sudden cardiac death poses a unique challenge to clinicians because it may be the only
symptom of an inherited heart condition. Indeed, inherited heart diseases can cause sudden …

Long QT syndrome, short QT syndrome, Brugada syndrome and catecholaminergic
polymorphic ventricular tachycardia are inherited primary electrical disorders that …

A prominent J wave is encountered in a number of life-threatening cardiac arrhythmia
syndromes, including the Brugada syndrome and early repolarization syndromes. Brugada …

Abstract In 1992, the Brugada syndrome (BrS) was recognized as a disease responsible for
sudden cardiac death, characterized by a right bundle-branch block with ST segment …

Brugada syndrome is a rare inherited arrhythmia syndrome leading to an increased risk of
sudden cardiac death, despite a structurally normal heart. Diagnosis is based on a specific …