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Vascular mechanotransduction
This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …
Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles
NR Tykocki, EM Boerman… - Comprehensive …, 2017 - pmc.ncbi.nlm.nih.gov
Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
Physiological temperature drives TRPM4 ligand recognition and gating
Temperature profoundly affects macromolecular function, particularly in proteins with
temperature sensitivity,. However, its impact is often overlooked in biophysical studies that …
temperature sensitivity,. However, its impact is often overlooked in biophysical studies that …
Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine
B Nilius, A Szallasi - Pharmacological reviews, 2014 - Elsevier
The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
[HTML][HTML] A structural overview of the ion channels of the TRPM family
The TRPM (transient receptor potential melastatin) family belongs to the superfamily of TRP
cation channels. The TRPM subfamily is composed of eight members that are involved in …
cation channels. The TRPM subfamily is composed of eight members that are involved in …
[PDF][PDF] An introduction to TRP channels
IS Ramsey, M Delling, DE Clapham - Annual review of …, 2006 - researchgate.net
AN INTRODUCTION TO TRP CHANNELS Page 1 Annu. Rev. Physiol. 2006. 68:619–47 doi:
10.1146/annurev.physiol.68.040204.100431 Copyright cO 2006 by Annual Reviews. All rights …
10.1146/annurev.physiol.68.040204.100431 Copyright cO 2006 by Annual Reviews. All rights …
[HTML][HTML] TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation
Collapse of membrane lipid asymmetry is a hallmark of blood coagulation. TMEM16F of the
TMEM16 family that includes TMEM16A/B Ca 2+-activated Cl− channels (CaCCs) is linked …
TMEM16 family that includes TMEM16A/B Ca 2+-activated Cl− channels (CaCCs) is linked …
TRPM channels in health and disease
Different cell channels and transporters tightly regulate cytoplasmic levels and the
intraorganelle distribution of cations. Perturbations in these processes lead to human …
intraorganelle distribution of cations. Perturbations in these processes lead to human …
Transient receptor potential cation channels in disease
The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family
Transient receptor potential (TRP) channels are a large family of ion channel proteins,
surpassed in number in mammals only by voltage-gated potassium channels. TRP channels …
surpassed in number in mammals only by voltage-gated potassium channels. TRP channels …