Ocular drug delivery: a comprehensive review

S Ahmed, MM Amin, S Sayed - AAPS PharmSciTech, 2023 - Springer
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

Recent advances of controlled drug delivery using microfluidic platforms

ST Sanjay, W Zhou, M Dou, H Tavakoli, L Ma… - Advanced drug delivery …, 2018 - Elsevier
Conventional systematically-administered drugs distribute evenly throughout the body, get
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …

Polymer-based carriers for ophthalmic drug delivery

JC Imperiale, GB Acosta, A Sosnik - Journal of controlled release, 2018 - Elsevier
Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …

Measurement, correlation and thermodynamic modeling of the solubility of Ketotifen fumarate (KTF) in supercritical carbon dioxide: Evaluation of PCP-SAFT equation …

G Sodeifian, NS Ardestani, SA Sajadian, HS Panah - Fluid phase equilibria, 2018 - Elsevier
Solubility measurement of desired solid component (s) represents a primary and crucial step
of feasibility study on production process of a nanoparticle drug through supercritical fluid …

Polymeric nanoparticles for increasing oral bioavailability of curcumin

A Umerska, C Gaucher, F Oyarzun-Ampuero… - Antioxidants, 2018 - mdpi.com
Despite the promising biological and antioxidant properties of curcumin, its medical
applications are limited due to poor solubility in water and low bioavailability. Polymeric …

Colloidal nanosystems with mucoadhesive properties designed for ocular topical delivery

B Silva, B São Braz, E Delgado, L Gonçalves - International Journal of …, 2021 - Elsevier
Over the last years, the scientific interest about topical ocular delivery targeting the posterior
segment of the eye has been increasing. This is probably due to the fact that this is a non …

[HTML][HTML] Preparation and characterization of colon-targeted pH/Time-dependent nanoparticles using anionic and cationic polymethacrylate polymers

Y Turanlı, F Acartürk - European Journal of Pharmaceutical Sciences, 2022 - Elsevier
Inflammatory bowel disease (IBD), which is a chronic inflammatory disease of the
gastrointestinal system, has two subtypes: Ulcerative Colitis (UC) and Crohn's Disease (CD) …

Microfluidics in drug delivery: review of methods and applications

M Rawas-Qalaji, R Cagliani, N Al-Hashimi… - Pharmaceutical …, 2023 - Taylor & Francis
Microfluidics technology has emerged as a promising methodology for the fabrication of a
wide variety of advanced drug delivery systems. Owing to its ability for accurate handling …

Mechanism for the nano-based drug delivery system

K Vinothini, M Rajan - Characterization and biology of nanomaterials for …, 2019 - Elsevier
Drug delivery nanocarrier units can take various structures, for example, tubes, globular
particles, and rods, and can fill in as flexible nanocarrier stages that can possibly, likewise …

Evaluation of anti-inflammatory impact of dexamethasone-loaded PCL-PEG-PCL micelles on endotoxin-induced uveitis in rabbits

M Alami-Milani, P Zakeri-Milani… - Pharmaceutical …, 2019 - Taylor & Francis
The aim of this study was to investigate the capability of polycaprolactone-polyethylene
glycol-polycaprolactone (PCL-PEG-PCL) micelles in improving the anti-inflammatory effects …