[HTML][HTML] Estradiol and cognitive function: past, present and future
A historical perspective on estradiol's enhancement of cognitive function is presented, and
research, primarily in animals, but also in humans, is reviewed. Data regarding the …
research, primarily in animals, but also in humans, is reviewed. Data regarding the …
Estrogens and phytoestrogens in body functions
Estrogens are the hormones of reproduction in women as well as of many other important
functions in the male and female body. They undergo significant changes in the different …
functions in the male and female body. They undergo significant changes in the different …
Neuron-derived estrogen regulates synaptic plasticity and memory
17β-estradiol (E2) is produced from androgens via the action of the enzyme aromatase. E2
is known to be made in neurons in the brain, but its precise functions in the brain are …
is known to be made in neurons in the brain, but its precise functions in the brain are …
Multivariate models of animal sex: breaking binaries leads to a better understanding of ecology and evolution
Synopsis “Sex” is often used to describe a suite of phenotypic and genotypic traits of an
organism related to reproduction. However, these traits—gamete type, chromosomal …
organism related to reproduction. However, these traits—gamete type, chromosomal …
Sex bias and omission in neuroscience research is influenced by research model and journal, but not reported NIH funding
GM Mamlouk, DM Dorris, LR Barrett… - Frontiers in …, 2020 - Elsevier
Neuroscience research has historically demonstrated sex bias that favors male over female
research subjects, as well as sex omission, which is the lack of reporting sex. Here we …
research subjects, as well as sex omission, which is the lack of reporting sex. Here we …
The importance of studying sex differences in disease: The example of multiple sclerosis
To date, scientific research has often focused on one sex, with assumptions that study of the
other sex would yield similar results. However, many diseases affect males and females …
other sex would yield similar results. However, many diseases affect males and females …
Steroid transport, local synthesis, and signaling within the brain: roles in neurogenesis, neuroprotection, and sexual behaviors
Sex steroid hormones are synthesized from cholesterol and exert pleiotropic effects notably
in the central nervous system. Pioneering studies from Baulieu and colleagues have …
in the central nervous system. Pioneering studies from Baulieu and colleagues have …
Inhibition of local estrogen synthesis in the hippocampus impairs hippocampal memory consolidation in ovariectomized female mice
The potent estrogen 17β-Estradiol (E 2) plays a critical role in mediating hippocampal
function, yet the precise mechanisms through which E 2 enhances hippocampal memory …
function, yet the precise mechanisms through which E 2 enhances hippocampal memory …
Insights into rapid modulation of neuroplasticity by brain estrogens
Converging evidence from cellular, electrophysiological, anatomic, and behavioral studies
suggests that the remodeling of synapse structure and function is a critical component of …
suggests that the remodeling of synapse structure and function is a critical component of …
Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions
In the last years there has been a considerable advance in the knowledge on the regulation
of astrocytes by sex steroids under physiological and pathological conditions. By the …
of astrocytes by sex steroids under physiological and pathological conditions. By the …