Heat shock proteins: dynamic biomolecules to counter plant biotic and abiotic stresses

S ul Haq, A Khan, M Ali, AM Khattak, WX Gai… - International journal of …, 2019 - mdpi.com
Due to the present scenario of climate change, plants have to evolve strategies to survive
and perform under a plethora of biotic and abiotic stresses, which restrict plant productivity …

Heat shock response and heat shock proteins: Current understanding and future opportunities in human diseases

MK Singh, Y Shin, S Ju, S Han, W Choe… - International Journal of …, 2024 - mdpi.com
The heat shock response is an evolutionarily conserved mechanism that protects cells or
organisms from the harmful effects of various stressors such as heat, chemicals toxins, UV …

[HTML][HTML] Hsp70 in redox homeostasis

H Zhang, W Gong, S Wu, S Perrett - Cells, 2022 - mdpi.com
Cellular redox homeostasis is precisely balanced by generation and elimination of reactive
oxygen species (ROS). ROS are not only capable of causing oxidation of proteins, lipids and …

Mechanisms of Hsp90 regulation

C Prodromou - Biochemical Journal, 2016 - portlandpress.com
Heat shock protein 90 (Hsp90) is a molecular chaperone that is involved in the activation of
disparate client proteins. This implicates Hsp90 in diverse biological processes that require …

[HTML][HTML] A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress

O Brandman, J Stewart-Ornstein, D Wong, A Larson… - Cell, 2012 - cell.com
The conserved transcriptional regulator heat shock factor 1 (Hsf1) is a key sensor of
proteotoxic and other stress in the eukaryotic cytosol. We surveyed Hsf1 activity in a genome …

Heat shock factors: integrators of cell stress, development and lifespan

M Åkerfelt, RI Morimoto, L Sistonen - Nature reviews Molecular cell …, 2010 - nature.com
Heat shock factors (HSFs) are essential for all organisms to survive exposures to acute
stress. They are best known as inducible transcriptional regulators of genes encoding …

[KÖNYV][B] Biochemical adaptation: mechanism and process in physiological evolution

PW Hochachka, GN Somero - 2002 - books.google.com
The study of biochemical adaption provides fascinating insights into how organisms" work"
and how they evolve to sustain physiological function under a vast array of environmental …

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

J Anckar, L Sistonen - Annual review of biochemistry, 2011 - annualreviews.org
To dampen proteotoxic stresses and maintain protein homeostasis, organisms possess a
stress-responsive molecular machinery that detects and neutralizes protein damage. A …

Hsp90 as a capacitor for morphological evolution

SL Rutherford, S Lindquist - Nature, 1998 - nature.com
The heat-shock protein Hsp90 supports diverse but specific signal transducers and lies at
the interface of several developmental pathways. We report here that when Drosophila …

Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators

RI Morimoto - Genes & development, 1998 - genesdev.cshlp.org
Our cells and tissues are challenged constantly by exposure to extreme conditions that
cause acute and chronic stress. Consequently, survival has necessitated the evolution of …