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Heat shock proteins: dynamic biomolecules to counter plant biotic and abiotic stresses
Due to the present scenario of climate change, plants have to evolve strategies to survive
and perform under a plethora of biotic and abiotic stresses, which restrict plant productivity …
and perform under a plethora of biotic and abiotic stresses, which restrict plant productivity …
Heat shock response and heat shock proteins: Current understanding and future opportunities in human diseases
MK Singh, Y Shin, S Ju, S Han, W Choe… - International Journal of …, 2024 - mdpi.com
The heat shock response is an evolutionarily conserved mechanism that protects cells or
organisms from the harmful effects of various stressors such as heat, chemicals toxins, UV …
organisms from the harmful effects of various stressors such as heat, chemicals toxins, UV …
[HTML][HTML] Hsp70 in redox homeostasis
H Zhang, W Gong, S Wu, S Perrett - Cells, 2022 - mdpi.com
Cellular redox homeostasis is precisely balanced by generation and elimination of reactive
oxygen species (ROS). ROS are not only capable of causing oxidation of proteins, lipids and …
oxygen species (ROS). ROS are not only capable of causing oxidation of proteins, lipids and …
Mechanisms of Hsp90 regulation
C Prodromou - Biochemical Journal, 2016 - portlandpress.com
Heat shock protein 90 (Hsp90) is a molecular chaperone that is involved in the activation of
disparate client proteins. This implicates Hsp90 in diverse biological processes that require …
disparate client proteins. This implicates Hsp90 in diverse biological processes that require …
[HTML][HTML] A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress
The conserved transcriptional regulator heat shock factor 1 (Hsf1) is a key sensor of
proteotoxic and other stress in the eukaryotic cytosol. We surveyed Hsf1 activity in a genome …
proteotoxic and other stress in the eukaryotic cytosol. We surveyed Hsf1 activity in a genome …
Heat shock factors: integrators of cell stress, development and lifespan
Heat shock factors (HSFs) are essential for all organisms to survive exposures to acute
stress. They are best known as inducible transcriptional regulators of genes encoding …
stress. They are best known as inducible transcriptional regulators of genes encoding …
[KÖNYV][B] Biochemical adaptation: mechanism and process in physiological evolution
PW Hochachka, GN Somero - 2002 - books.google.com
The study of biochemical adaption provides fascinating insights into how organisms" work"
and how they evolve to sustain physiological function under a vast array of environmental …
and how they evolve to sustain physiological function under a vast array of environmental …
Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease
J Anckar, L Sistonen - Annual review of biochemistry, 2011 - annualreviews.org
To dampen proteotoxic stresses and maintain protein homeostasis, organisms possess a
stress-responsive molecular machinery that detects and neutralizes protein damage. A …
stress-responsive molecular machinery that detects and neutralizes protein damage. A …
Hsp90 as a capacitor for morphological evolution
SL Rutherford, S Lindquist - Nature, 1998 - nature.com
The heat-shock protein Hsp90 supports diverse but specific signal transducers and lies at
the interface of several developmental pathways. We report here that when Drosophila …
the interface of several developmental pathways. We report here that when Drosophila …
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
RI Morimoto - Genes & development, 1998 - genesdev.cshlp.org
Our cells and tissues are challenged constantly by exposure to extreme conditions that
cause acute and chronic stress. Consequently, survival has necessitated the evolution of …
cause acute and chronic stress. Consequently, survival has necessitated the evolution of …