C-glycosides and aza-C-glycosides as potential glycosidase and glycosyltransferase inhibitors

W Zou - Current topics in medicinal chemistry, 2005 - ingentaconnect.com
Glycosylation as one of most important post-translational modification of gene products is
often critical to specific cellular biological functions. Since elevated glycoprocessing enzyme …

The effect of electrostatic interactions on conformational equilibria of multiply substituted tetrahydropyran oxocarbenium ions

MT Yang, KA Woerpel - The Journal of organic chemistry, 2009 - ACS Publications
The three-dimensional structures of dioxocarbenium ions related to glycosyl cations were
determined by an analysis of spectroscopic, computational, and reactivity data. Hypothetical …

1, 5-Hydrogen atom transfer/Surzur–Tanner rearrangement: a radical cascade approach for the synthesis of 1, 6-dioxaspiro [4.5] decane and 6, 8-dioxabicyclo [3.2. 1] …

EI León, Á Martín, AS Montes… - The Journal of …, 2021 - ACS Publications
The 1, 5-HAT–1, 2-(ester) alkyl radical migration (Surzur–Tanner rearrangement)
radical/polar sequence triggered by alkoxyl radicals has been studied on a series of C …

Chemically-modified polysaccharide extract derived from Leucaena leucocephala alters Raw 264.7 murine macrophage functions

AM Gamal-Eldeen, H Amer, WA Helmy… - International …, 2007 - Elsevier
In this study, a chemical modification of the polysaccharides extract (E) derived from
Leucaena leucocephala seeds was performed to prepare C-glycosidic 2-propanol derivative …

A convenient synthesis of novel pyranosyl homo-C-nucleosides and their antidiabetic activities

SS Bisht, N Jaiswal, A Sharma, S Fatima… - Carbohydrate …, 2011 - Elsevier
A series of pyranosyl homo-C-nucleosides have been synthesized by reaction of butenonyl
C-glycosides (5a–5j, and 8) and cyanoacetamide in presence of t-BuOK followed by further …

Gold (i)-catalyzed C-glycosylation of glycosyl ortho-alkynylbenzoates: the role of the moisture sequestered by molecular sieves

X Chen, Q Wang, B Yu - Chemical Communications, 2016 - pubs.rsc.org
C-Glycosylation of glycosyl ortho-hexynylbenzoates with allyltrimethylsilane or silyl enol
ethers could proceed smoothly under the catalysis of Ph3PAuNTf2 to provide the …

Influence of the O3 Protecting Group on Stereoselectivity in the Preparation of C-Mannopyranosides with 4,6-O-Benzylidene Protected Donors

D Crich, I Sharma - The Journal of organic chemistry, 2010 - ACS Publications
α-C-Glucopyranosides and mannopyranosides are obtained in 65− 85% yields from 4, 6-O-
benzylidene-protected glucosyl and mannosyl thioglycosides bearing ester functionality at …

InCl3 Catalyzed Highly Diastereoselective [3 + 2] Cycloaddition of 1,2-Cyclopropanated Sugars with Aldehydes: A Straightforward Synthesis of Persubstituted Bis …

X Ma, Q Tang, J Ke, X Yang, J Zhang, H Shao - Organic letters, 2013 - ACS Publications
A mild and efficient strategy for the construction of persubstituted bis-tetrahydrofuran and
perhydrofuro [2, 3-b] pyran derivatives has been developed. Persubstituted cyclization …

Synthesis and solvent driven self-aggregation studies of meso-“C-glycoside”-porphyrin derivatives

P Štěpánek, M Dukh, D Šaman, J Moravcová… - Organic & …, 2007 - pubs.rsc.org
New types of porphyrin derivatives bearing “C-glycoside” moieties, either in 5, 10, 15, 20-or
in 5, 15-meso-positions, were prepared and fully characterized. The presence of the …

Antiproliferative and Cancer-chemopreventive Properties of Sulfated Glycosylated Extract Derived from Leucaena leucocephala.

AM Gamal-Eldeen, H Amer, WA Helmy… - Indian Journal of …, 2007 - search.ebscohost.com
This work aimed to prove that simple chemical modification could provide new cancer
chemopreventive and/or anticancer properties to the inactive extracted polysaccharide …