[HTML][HTML] Out of Africa: origins and evolution of the human malaria parasites Plasmodium falciparum and Plasmodium vivax

DE Loy, W Liu, Y Li, GH Learn, LJ Plenderleith… - International journal for …, 2017 - Elsevier
Plasmodium falciparum and Plasmodium vivax account for more than 95% of all human
malaria infections, and thus pose a serious public health challenge. To control and …

Host-malaria parasite interactions and impacts on mutual evolution

X Su, C Zhang, DA Joy - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …

Origin of the human malaria parasite Plasmodium falciparum in gorillas

W Liu, Y Li, GH Learn, RS Rudicell, JD Robertson… - Nature, 2010 - nature.com
Plasmodium falciparum is the most prevalent and lethal of the malaria parasites infecting
humans, yet the origin and evolutionary history of this important pathogen remain …

Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria

TD Otto, A Gilabert, T Crellen, U Böhme… - Nature …, 2018 - nature.com
Plasmodium falciparum, the most virulent agent of human malaria, shares a recent common
ancestor with the gorilla parasite Plasmodium praefalciparum. Little is known about the other …

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

GG Rutledge, U Böhme, M Sanders, AJ Reid… - Nature, 2017 - nature.com
Elucidation of the evolutionary history and interrelatedness of Plasmodium species that
infect humans has been hampered by a lack of genetic information for three human-infective …

The origin of malignant malaria

SM Rich, FH Leendertz, G Xu… - Proceedings of the …, 2009 - National Acad Sciences
Plasmodium falciparum, the causative agent of malignant malaria, is among the most severe
human infectious diseases. The closest known relative of P. falciparum is a chimpanzee …

Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria

SA Sundararaman, LJ Plenderleith, W Liu… - Nature …, 2016 - nature.com
African apes harbour at least six Plasmodium species of the subgenus Laverania, one of
which gave rise to human Plasmodium falciparum. Here we use a selective amplification …

Why Plasmodium vivax and Plasmodium falciparum are so different? A tale of two clades and their species diversities

AA Escalante, AS Cepeda, MA Pacheco - Malaria Journal, 2022 - Springer
The global malaria burden sometimes obscures that the genus Plasmodium comprises
diverse clades with lineages that independently gave origin to the extant human parasites …

On the Diversity of Malaria Parasites in African Apes and the Origin of Plasmodium falciparum from Bonobos

S Krief, AA Escalante, MA Pacheco, L Mugisha… - PLoS …, 2010 - journals.plos.org
The origin of Plasmodium falciparum, the etiological agent of the most dangerous forms of
human malaria, remains controversial. Although investigations of homologous parasites in …

African great apes are natural hosts of multiple related malaria species, including Plasmodium falciparum

F Prugnolle, P Durand, C Neel… - Proceedings of the …, 2010 - National Acad Sciences
Plasmodium reichenowi, a chimpanzee parasite, was until very recently the only known
close relative of Plasmodium falciparum, the most virulent agent of human malaria. Recently …