The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications
B Zingales, MA Miles, DA Campbell… - Infection, genetics and …, 2012 - Elsevier
The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …
nature for millions of years. The human infection, named Chagas disease, is a major public …
Kinetoplastids: related protozoan pathogens, different diseases
Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma
and Leishmania, which are human pathogens with devastating health and economic effects …
and Leishmania, which are human pathogens with devastating health and economic effects …
TriTrypDB: a functional genomic resource for the Trypanosomatidae
ABSTRACT TriTrypDB (http://tritrypdb. org) is an integrated database providing access to
genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex …
genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex …
The Genome of the African Trypanosome Trypanosoma brucei
African trypanosomes cause human slee** sickness and livestock trypanosomiasis in sub-
Saharan Africa. We present the sequence and analysis of the 11 megabase-sized …
Saharan Africa. We present the sequence and analysis of the 11 megabase-sized …
The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease
Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the
diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 …
diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 …
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism
RL Krauth-Siegel, MA Comini - … et Biophysica Acta (BBA)-General Subjects, 2008 - Elsevier
Trypanosomes and leishmania, the causative agents of several tropical diseases, possess a
unique redox metabolism which is based on trypanothione. The bis (glutathionyl) …
unique redox metabolism which is based on trypanothione. The bis (glutathionyl) …
Pathogenesis of chagas' disease: parasite persistence and autoimmunity
ARL Teixeira, MM Hecht, MC Guimaro… - Clinical microbiology …, 2011 - Am Soc Microbiol
Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
Energy metabolism of trypanosomatids: adaptation to available carbon sources
Some development stages of the trypanosomatid protozoan parasites are well adapted to in
vitro culture. They can be maintained in rich medium containing large excess of glucose and …
vitro culture. They can be maintained in rich medium containing large excess of glucose and …
Trypanosoma cruzi surface mucins: host-dependent coat diversity
CA Buscaglia, VA Campo, ACC Frasch… - Nature Reviews …, 2006 - nature.com
The surface of the protozoan parasite Trypanosoma cruzi is covered in mucins, which
contribute to parasite protection and to the establishment of a persistent infection. Their …
contribute to parasite protection and to the establishment of a persistent infection. Their …
Evasion of the Immune Response by Trypanosoma cruzi during Acute Infection
MS Cardoso, JL Reis-Cunha… - Frontiers in …, 2016 - frontiersin.org
Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical disease
that affects millions of people mainly in Latin America. To establish a life-long infection, T …
that affects millions of people mainly in Latin America. To establish a life-long infection, T …