Mathematical and computational modelling of skin biophysics: a review

G Limbert - Proceedings of the Royal Society A …, 2017 - royalsocietypublishing.org
The objective of this paper is to provide a review on some aspects of the mathematical and
computational modelling of skin biophysics, with special focus on constitutive theories based …

The virtual physiological human: ten years after

M Viceconti, P Hunter - Annual review of biomedical …, 2016 - annualreviews.org
Biomedical research and clinical practice are struggling to cope with the growing complexity
that the progress of health care involves. The most challenging diseases, those with the …

A mechanistic insight into the mechanical role of the stratum corneum during stretching and compression of the skin

MF Leyva-Mendivil, A Page, NW Bressloff… - Journal of the Mechanical …, 2015 - Elsevier
The study of skin biophysics has largely been driven by consumer goods, biomedical and
cosmetic industries which aim to design products that efficiently interact with the skin and/or …

[PDF][PDF] Thermobiological Mathematical Model for the study of temperature response after cooling effects

V Kumar, SR Shah - ssrg, International Journal of Applied physics, 2022 - researchgate.net
An thermobiological mathematical model is developed to study the recovery of skin tissue to
the ambient temperature after the exposure of skin to cold temperature till the skin reaches …

Mechano-biological and bio-mechanical pathways in cutaneous wound healing

M Pensalfini, AB Tepole - PLoS computational biology, 2023 - journals.plos.org
Injuries to the skin heal through coordinated action of fibroblast-mediated extracellular
matrix (ECM) deposition, ECM remodeling, and wound contraction. Defects involving the …

A biphasic multilayer computational model of human skin

D Sachs, A Wahlsten, S Kozerke, G Restivo… - … and modeling in …, 2021 - Springer
The present study investigates the layer-specific mechanical behavior of human skin.
Motivated by skin's histology, a biphasic model is proposed which differentiates between …

A large deformation model for quasi-static to high strain rate response of a rate-stiffening soft polymer

A Konale, Z Ahmed, P Wanchoo… - International Journal of …, 2023 - Elsevier
Polyborosiloxane (PBS) is an important rate-stiffening soft polymer with dynamic, reversible
crosslinks used in applications ranging from self-healing sensing and actuation to body and …

Arterial tissues and their inflammatory response to collagen damage: a continuum in silico model coupling nonlinear mechanics, molecular pathways, and cell …

M Gierig, P Wriggers, M Marino - Computers in Biology and Medicine, 2023 - Elsevier
Damage in soft biological tissues causes an inflammatory reaction that initiates a chain of
events to repair the tissue. This work presents a continuum model and its in silico …

[HTML][HTML] On modeling the multiscale mechanobiology of soft tissues: Challenges and progress

Y Guo, MRK Mofrad, AB Tepole - Biophysics Reviews, 2022 - pubs.aip.org
Tissues grow and remodel in response to mechanical cues, extracellular and intracellular
signals experienced through various biological events, from the develo** embryo to …

Computational model of damage-induced growth in soft biological tissues considering the mechanobiology of healing

M Gierig, P Wriggers, M Marino - Biomechanics and Modeling in …, 2021 - Springer
Healing in soft biological tissues is a chain of events on different time and length scales. This
work presents a computational framework to capture and couple important mechanical …