Tumor surgical resection is the major strategy for cancer treatment. Meanwhile,
perioperative treatment especially the postoperative adjuvant anticancer strategies play …

Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high
recurrence and poor prognosis. The standard of care, surgical resection followed by …

Immunotherapies have revolutionized intervention strategies for many primary cancers, but
have not improved the outcomes of glioblastoma multiforme (GBM), which remains one of …

The unique cancer-associated immunosuppression in brain, combined with a paucity of
infiltrating T cells, contributes to the low response rate and poor treatment outcomes of T cell …

Design of endogenous stimuli-responsive amino acids allows for precisely modulating
proteins or peptides under a biological microenvironment and thereby regulating their …

A major challenge of cancer immunotherapy is to develop delivery strategies that can
effectively and safely augment the immune system's antitumor response. Here, we report on …

The central nervous system (CNS) controls the acquisition and processing of peripheral
information to manage the behaviors of organisms. CNS disorders, including CNS injuries …

One of the main challenges in the development of long-acting injectables for HIV treatment
is the limited duration of drug release, which results in the need for frequent dosing and …

Local chemotherapy is a clinically proven strategy in treating malignant brain tumors. Its
benefits, however, are largely limited by the rapid release and clearance of therapeutic …

Self-assembled nanostructures are highly promising for controlled delivery of therapeutic
and diagnostic agents. However, for conventional drug delivery nanosystems, there exist …