Identification of common genetic risk variants for autism spectrum disorder
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
Adult zebrafish as a model organism for behavioural genetics
W Norton, L Bally-Cuif - BMC neuroscience, 2010 - Springer
Recent research has demonstrated the suitability of adult zebrafish to model some aspects
of complex behaviour. Studies of reward behaviour, learning and memory, aggression …
of complex behaviour. Studies of reward behaviour, learning and memory, aggression …
Linking genes to brain, behavior and neurological diseases: what can we learn from zebrafish?
S Guo - Genes, Brain and Behavior, 2004 - Wiley Online Library
How our brain is wired and subsequently generates functional output, ranging from sensing
and locomotion to emotion, decision‐making and learning and memory, remains poorly …
and locomotion to emotion, decision‐making and learning and memory, remains poorly …
Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo
Within the vertebrate nervous system, the presence of many different lineages of neurons
and glia complicates the molecular characterization of single neuronal populations. In order …
and glia complicates the molecular characterization of single neuronal populations. In order …
Fezl is required for the birth and specification of corticospinal motor neurons
The molecular mechanisms controlling the differentiation of neural progenitors into distinct
subtypes of neurons during neocortical development are unknown. Here, we report that Fezl …
subtypes of neurons during neocortical development are unknown. Here, we report that Fezl …
Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex
B Chen, LR Schaevitz… - Proceedings of the …, 2005 - National Acad Sciences
During the development of the cerebral cortex, progenitor cells produce neurons that
migrate to laminar positions appropriate for their birth dates, adopt specific neuronal …
migrate to laminar positions appropriate for their birth dates, adopt specific neuronal …
Molecular psychiatry of zebrafish
Due to their well-characterized neural development and high genetic homology to
mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field …
mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field …
An injury-induced serotonergic neuron subpopulation contributes to axon regrowth and function restoration after spinal cord injury in zebrafish
CX Huang, Y Zhao, J Mao, Z Wang, L Xu… - Nature …, 2021 - nature.com
Spinal cord injury (SCI) interrupts long-projecting descending spinal neurons and disrupts
the spinal central pattern generator (CPG) that controls locomotion. The intrinsic …
the spinal central pattern generator (CPG) that controls locomotion. The intrinsic …
Development of the hypothalamus: conservation, modification and innovation
The hypothalamus, which regulates fundamental aspects of physiological homeostasis and
behavior, is a brain region that exhibits highly conserved anatomy across vertebrate …
behavior, is a brain region that exhibits highly conserved anatomy across vertebrate …
Can zebrafish be used as a model to study the neurodevelopmental causes of autism?
V Tropepe, HL Sive - Genes, Brain and Behavior, 2003 - Wiley Online Library
The zebrafish has proven to be an excellent model for analyzing issues of vertebrate
development. In this review we ask whether the zebrafish is a viable model for analyzing the …
development. In this review we ask whether the zebrafish is a viable model for analyzing the …