Microfluidics expands the synthetic space such as heat transfer, mass transport, and reagent
consumption to conditions not easily achievable in conventional batch processes …

Single-molecule spectroscopy has developed into an important method for probing protein
structure and dynamics, especially in structurally heterogeneous systems. A broad range of …

Nuclear pore complexes (NPCs) regulate all cargo traffic across the nuclear envelope. The
transport conduit of NPCs is highly enriched in disordered phenylalanine/glycine-rich …

Modern microflow cytometers are sophisticated instruments capable of measuring multiple
physical characteristics of a single cell simultaneously as the cells flow in suspension …

Novel applications of micro total analysis systems (μTAS) are addressing fundamental
biological questions, creating new biomedical reagents, and develo** innovative cell and …

Single-entity (or digital) measurements enhance sensitivity (10-to 100-fold improvement)
and uncover heterogeneity within a population (one event in 100 to 10,000). Many biological …

Three-dimensional (3D) continuous microparticle focusing has been achieved in a single-
layer polydimethylsiloxane (PDMS) microfluidic channel using a standing surface acoustic …

A novel design is presented for a chaotic micromixer using two-layer serpentine crossing
microchannels. The performance of the micromixer was analyzed both numerically and …

Compartmentalization of biochemical components, interactions, and reactions is critical for
the function of cells. While intracellular partitioning of molecules via membranes has been …

Efficient chaotic microdevices have major importance across many potential applications in
industrial processes and operations, which form essential parts of microfluidic devices. In …