HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management
Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …
Immune landscape of viral-and carcinogen-driven head and neck cancer
Head and neck squamous cell carcinoma (HNSCC) arises through exposure to
environmental carcinogens or malignant transformation by human papillomavirus (HPV) …
environmental carcinogens or malignant transformation by human papillomavirus (HPV) …
Rapid clearance profile of plasma circulating tumor HPV type 16 DNA during chemoradiotherapy correlates with disease control in HPV-associated oropharyngeal …
Purpose: To identify a profile of circulating tumor human papilloma virus (HPV) DNA
(ctHPVDNA) clearance kinetics that is associated with disease control after …
(ctHPVDNA) clearance kinetics that is associated with disease control after …
Intratumoral heterogeneity and clonal evolution induced by HPV integration
The human papillomavirus (HPV) genome is integrated into host DNA in most HPV-positive
cancers, but the consequences for chromosomal integrity are unknown. Continuous long …
cancers, but the consequences for chromosomal integrity are unknown. Continuous long …
[HTML][HTML] An interpretable machine learning prognostic system for risk stratification in oropharyngeal cancer
Background The optimal management of oropharyngeal squamous cell carcinoma (OPSCC)
includes both surgical and non-surgical, that is,(chemo) radiotherapy treatment options and …
includes both surgical and non-surgical, that is,(chemo) radiotherapy treatment options and …
Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors
We analyzed transcriptional data from 104 HPV+ (Human papillomavirus) HNSCC (head
and neck squamous cell carcinoma) tumors together with two publicly available sources to …
and neck squamous cell carcinoma) tumors together with two publicly available sources to …
Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
M Kamal, S Lameiras, M Deloger, A Morel… - British journal of …, 2021 - nature.com
Background Cervical cancer (CC) remains a leading cause of gynaecological cancer-
related mortality with infection by human papilloma virus (HPV) being the most important risk …
related mortality with infection by human papilloma virus (HPV) being the most important risk …
[HTML][HTML] ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization
ATRX, a chromatin remodeler protein, is recurrently mutated in H3F3A-mutant pediatric
glioblastoma (GBM) and isocitrate dehydrogenase (IDH)-mutant grade 2/3 adult glioma …
glioblastoma (GBM) and isocitrate dehydrogenase (IDH)-mutant grade 2/3 adult glioma …
Biology of HPV mediated carcinogenesis and tumor progression
Human papillomavirus (HPV) is a ubiquitous DNA virus that infects squamous epithelia.
Though HPV only encodes 8 genes, it is capable of causing cellular transformation and …
Though HPV only encodes 8 genes, it is capable of causing cellular transformation and …