Coherent light scattering from cellular dynamics in living tissues

DD Nolte - Reports on Progress in Physics, 2024‏ - iopscience.iop.org
This review examines the biological physics of intracellular transport probed by the coherent
optics of dynamic light scattering from optically thick living tissues. Cells and their …

Expanding applications, accuracy, and interpretation of laser speckle contrast imaging of cerebral blood flow

SMS Kazmi, LM Richards, CJ Schrandt… - Journal of Cerebral …, 2015‏ - journals.sagepub.com
Laser speckle contrast imaging (LSCI) provides a rapid characterization of cortical flow
dynamics for functional monitoring of the microcirculation. The technique stems from …

Bessel beam optical coherence microscopy enables multiscale assessment of cerebrovascular network morphology and function

L Glandorf, B Wittmann, J Droux, C Glück… - Light: Science & …, 2024‏ - nature.com
Understanding the morphology and function of large-scale cerebrovascular networks is
crucial for studying brain health and disease. However, reconciling the demands for imaging …

Dynamic light scattering and laser speckle contrast imaging of the brain: theory of the spatial and temporal statistics of speckle pattern evolution

B Liu, D Postnov, DA Boas, X Cheng - Biomedical Optics Express, 2024‏ - opg.optica.org
Dynamic light scattering (DLS) and laser speckle contrast imaging (LSCI) are closely related
techniques that exploit the statistics of speckle patterns, which can be utilized to measure …

Optical coherence tomography: basic concepts and applications in neuroscience research

M Ibne Mokbul - Journal of medical engineering, 2017‏ - Wiley Online Library
Optical coherence tomography is a micrometer‐scale imaging modality that permits label‐
free, cross‐sectional imaging of biological tissue microstructure using tissue backscattering …

Cortical microvascular blood flow velocity map** by combining dynamic light scattering optical coherence tomography and two-photon microscopy

Q Pian, M Alfadhel, J Tang, GV Lee, B Li… - Journal of …, 2023‏ - spiedigitallibrary.org
Significance The accurate large-scale map** of cerebral microvascular blood flow velocity
is crucial for a better understanding of cerebral blood flow (CBF) regulation. Although optical …

Chronic monitoring of vascular progression after ischemic stroke using multiexposure speckle imaging and two-photon fluorescence microscopy

CJ Schrandt, SMS Kazmi, TA Jones… - Journal of Cerebral …, 2015‏ - journals.sagepub.com
Monitoring the progression of the vascular structure and cerebral blood flow (CBF) after
brain injury is vital to understand the neurovascular recovery process. Multiexposure …

Visible spectrum extended-focus optical coherence microscopy for label-free sub-cellular tomography

PJ Marchand, A Bouwens, D Szlag… - Biomedical optics …, 2017‏ - opg.optica.org
We present a novel extended-focus optical coherence microscope (OCM) attaining 0.7 μm
axial and 0.4 μm lateral resolution maintained over a depth of 40 μm, while preserving the …

Multiple-capillary measurement of RBC speed, flux, and density with optical coherence tomography

J Lee, W Wu, F Lesage… - Journal of Cerebral Blood …, 2013‏ - journals.sagepub.com
As capillaries exhibit heterogeneous and fluctuating dynamics even during baseline, a
technique measuring red blood cell (RBC) speed and flux over many capillaries at the same …

Quantitative technique for robust and noise-tolerant speed measurements based on speckle decorrelation in optical coherence tomography

N Uribe-Patarroyo, M Villiger, BE Bouma - Optics express, 2014‏ - opg.optica.org
Intensity-based techniques in optical coherence tomography (OCT), such as those based on
speckle decorrelation, have attracted great interest for biomedical and industrial applications …