Aspects of immune dysfunction in end-stage renal disease
S Kato, M Chmielewski, H Honda… - Clinical Journal of the …, 2008 - journals.lww.com
End-stage renal disease (ESRD) is associated with significantly increased morbidity and
mortality resulting from cardiovascular disease (CVD) and infections, accounting for 50 …
mortality resulting from cardiovascular disease (CVD) and infections, accounting for 50 …
Immune cell dysfunction and inflammation in end-stage renal disease
MGH Betjes - Nature Reviews Nephrology, 2013 - nature.com
Uraemia causes inflammation and reduces immune system function as evidenced by an
increased risk of viral-associated cancers, increased susceptibility to infections and …
increased risk of viral-associated cancers, increased susceptibility to infections and …
Integrative physiology of pneumonia
Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …
outcome of lower respiratory infection is determined by the degrees to which immunity is …
FGF23 signaling impairs neutrophil recruitment and host defense during CKD
J Rossaint, J Oehmichen, H Van Aken… - The Journal of …, 2016 - Am Soc Clin Investig
Chronic kidney disease (CKD) has been associated with impaired host response and
increased susceptibility to infections. Leukocyte recruitment during inflammation must be …
increased susceptibility to infections. Leukocyte recruitment during inflammation must be …
FGF23 actions on target tissues—with and without klotho
B Richter, C Faul - Frontiers in endocrinology, 2018 - frontiersin.org
Fibroblast growth factor (FGF) 23 is a phosphaturic hormone whose physiologic actions on
target tissues are mediated by FGF receptors (FGFR) and klotho, which functions as a co …
target tissues are mediated by FGF receptors (FGFR) and klotho, which functions as a co …
[HTML][HTML] Risk factors for chronic biofilm-related infection associated with implanted medical devices
Background The use of implanted medical devices is associated with a small but clinically
important risk of foreign body infection. A key question is: why do some patients develop …
important risk of foreign body infection. A key question is: why do some patients develop …
Association between periodontitis and chronic kidney disease
K Parsegian, D Randall, M Curtis… - Periodontology …, 2022 - Wiley Online Library
Periodontitis and chronic kidney disease are chronic conditions with high community
prevalence across the world. Patients with chronic kidney disease have been noted to have …
prevalence across the world. Patients with chronic kidney disease have been noted to have …
Clinical epidemiology of infectious disease among patients with chronic kidney disease
J Ishigami, K Matsushita - Clinical and experimental nephrology, 2019 - Springer
Infectious disease is recognized as an important complication among patients with end-
stage renal disease, contributing to excess morbidity and health care costs. However, recent …
stage renal disease, contributing to excess morbidity and health care costs. However, recent …
Soluble uric acid inhibits β2 integrin–mediated neutrophil recruitment in innate immunity
Q Ma, R Immler, M Pruenster… - Blood, The Journal …, 2022 - ashpublications.org
Neutrophils are key players during host defense and sterile inflammation. Neutrophil
dysfunction is a characteristic feature of the acquired immunodeficiency during kidney …
dysfunction is a characteristic feature of the acquired immunodeficiency during kidney …
Secondary immunodeficiency related to kidney disease (SIDKD)—definition, unmet need, and mechanisms
S Steiger, J Rossaint, A Zarbock… - Journal of the American …, 2022 - journals.lww.com
Kidney disease is a known risk factor for poor outcomes of COVID-19 and many other
serious infections. Conversely, infection is the second most common cause of death in …
serious infections. Conversely, infection is the second most common cause of death in …