Background Total neoadjuvant therapy (TNT) is a novel approach for locally advanced rectal
cancer (LARC), which attempts to deliver both systemic chemotherapy and neoadjuvant …

Colorectal cancer (CRC) is the third most diagnosed cancer and the second leading cause
of cancer-related mortality in the United States. Across the globe, people in the age group …

PURPOSE Total neoadjuvant therapy is a new paradigm for rectal cancer treatment. Optimal
scheduling of preoperative chemoradiotherapy (CRT) and chemotherapy remains to be …

BACKGROUND: Adding modified FOLFOX6 (folinic acid, fluorouracil, and oxaliplatin) after
chemoradiotherapy and lengthening the chemoradiotherapy-to-surgery interval is …

In recent years, hepatitis B core protein virus‐like particle (HBc VLP) is an impressive
biomaterial, which has attracted considerable attention due to favorable properties such as …

Background The standard of care for the treatment of locally advanced rectal cancer (LARC)
results in an excellent local disease control but the metastasis rates remain high. PRODIGE …

Objectives Stratification of microsatellite instability (MSI) status in patients with colorectal
cancer (CRC) improves clinical decision-making for cancer treatment. The present study …

Objective This meta‐analysis aims to compare the effects of early palliative care on patients
with incurable cancer with those of standard oncologic care or on‐demand palliative care …

Background Advances in surgical technique and the development of combined-modality
therapy have led to significantly improved local control in rectal cancer. Distant failure rates …

The prognosis of pancreatic adenocarcinoma is dismal. Hence, advances in
multidisciplinary treatment strategies, including surgery, are urgently needed. Early …