Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

More than half a century ago researchers thought that d-amino acids had a minor function
compared to l-enantiomers in biological processes. Many evidences have shown that d …

Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …

From a structural perspective, the predominant glial cell of the central nervous system, the
astrocyte, is positioned to regulate synaptic transmission and neurovascular coupling: the …

Functional activity of N-methyl-d-aspartate (NMDA) receptors requires both glutamate
binding and the binding of an endogenous coagonist that has been presumed to be glycine …

The NMDA receptor is a key player in excitatory transmission and synaptic plasticity in the
central nervous system. Its activation requires the binding of both glutamate and a coagonist …

A labor of love and enthusiasm as well as deep scientific knowledge, Right Hand, Left Hand
takes the reader on a trip through history, around the world, and into the cosmos, to explore …

Although d amino acids are prominent in bacteria, they generally are thought not to occur in
mammals. Recently, high levels of d-serine have been found in mammalian brain where it …

Dopamine (DA) and glutamate neurotransmission are strongly implicated in schizophrenia
pathophysiology. While most studies focus on contributions of neurons that release only DA …

Astrocytes are found throughout the brain where they make extensive contacts with neurons
and synapses. Astrocytes are known to display intracellular Ca2+ signals and release …