[PDF][PDF] Brucella–virulence factors, pathogenesis and treatment

P Głowacka, D Żakowska, K Naylor… - Polish journal of …, 2018 - sciendo.com
Brucellae are Gram-negative, small rods infecting mammals and capable of causing disease
called brucellosis. The infection results in abortion and sterility in domestic animals (sheeps …

Uncovering the Hidden Credentials of Brucella Virulence

RM Roop, IS Barton, D Hopersberger… - … and Molecular Biology …, 2021 - journals.asm.org
Bacteria in the genus Brucella are important human and veterinary pathogens. The abortion
and infertility they cause in food animals produce economic hardships in areas where the …

Internal affairs: investigating the Brucella intracellular lifestyle

K von Bargen, JP Gorvel… - FEMS microbiology …, 2012 - academic.oup.com
Bacteria of the genus Brucella are Gram-negative pathogens of several animal species that
cause a zoonotic disease in humans known as brucellosis or Malta fever. Within their hosts …

Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host

RM Roop, JM Gaines, ES Anderson… - Medical microbiology …, 2009 - Springer
Brucella strains produce abortion and infertility in their natural hosts and a zoonotic disease
in humans known as undulant fever. These bacteria do not produce classical virulence …

Host Immune Responses to the Intracellular Bacteria Brucella: Does the Bacteria Instruct the Host to Facilitate Chronic Infection?

CL Baldwin, R Goenka - Critical Reviews™ in Immunology, 2006 - dl.begellhouse.com
Brucella spp. are intracellular gram-negative bacteria that include a number of virulent
species that cause chronic infections in a variety of mammalian hosts. Human infections are …

Superoxide dismutase: A key enzyme for the survival of intracellular pathogens in host

R Maurya, M Namdeo - Reactive Oxygen Species, 2021 - books.google.com
Superoxide dismutase (SOD) is a crucial enzyme required to maintain the redox potential of
the cells. It plays a vital role in protecting normal cells from reactive oxygen species (ROS) …

Detection and Quantification of Superoxide Formed within the Periplasm of Escherichia coli

S Korshunov, JA Imlay - Journal of bacteriology, 2006 - journals.asm.org
Many gram-negative bacteria harbor a copper/zinc-containing superoxide dismutase
(CuZnSOD) in their periplasms. In pathogenic bacteria, one role of this enzyme may be to …

Brucella: a pathogen without classic virulence genes

MN Seleem, SM Boyle, N Sriranganathan - Veterinary microbiology, 2008 - Elsevier
The first species of Brucella was isolated and characterized almost 120 years ago and
recently the complete nucleotide sequences of the genomes of a number of well …

Subversion of innate immune responses by Brucella through the targeted degradation of the TLR signaling adapter, MAL

D Sengupta, A Koblansky, J Gaines… - The journal of …, 2010 - journals.aai.org
Gram-negative bacteria belonging to the Brucella species cause chronic infections that can
result in undulant fever, arthritis, and osteomyelitis in humans. Remarkably, Brucella sp …

Superoxide Dismutase B Gene (sodB)-Deficient Mutants of Francisella tularensis Demonstrate Hypersensitivity to Oxidative Stress and Attenuated Virulence

CS Bakshi, M Malik, K Regan, JA Melendez… - Journal of …, 2006 - journals.asm.org
ABSTRACT A Francisella tularensis live vaccine strain mutant (sodBFt) with reduced Fe-
superoxide dismutase gene expression was generated and found to exhibit decreased sodB …