Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

Loss of photoreceptors due to retinal degeneration is a major cause of blindness in the
developed world. While no effective treatment is currently available, cell replacement …

Purpose.: Alzheimer's disease (AD) is the most common neurodegenerative disorder
characterized by progressive decline in learning, memory, and executive functions. In …

Vision loss in glaucoma is caused by progressive dysfunction of retinal ganglion cells
(RGCs) and optic nerve atrophy. Here, we investigated the effectiveness of BDNF treatment …

Retinal prostheses aim to restore vision to blind individuals suffering from retinal diseases
such as retinitis pigmentosa and age-related macular degeneration. These devices function …

Retinal ganglion cells (RGCs) may be regarded as a target biomarker in Alzheimer's
disease (AD). We therefore explored the possibility that RGC degeneration, rather than cell …

Sensory deafferentation resulting from the loss of photoreceptors during retinal
degeneration (rd) is often accompanied by a paradoxical increase in spontaneous activity …

Inherited or acquired photoreceptor degenerations, one of the leading causes of irreversible
blindness in the world, are a group of retinal disorders that initially affect rods and cones …

Retinitis Pigmentosa (RP) reflects a range of inherited retinal disorders which involve
photoreceptor degeneration and retinal pigmented epithelium dysfunction. Despite the …

Retinal degenerative diseases such as retinitis pigmentosa cause a progressive loss of
photoreceptors that eventually prevents the affected person from perceiving visual …