RNA-extraction-free nano-amplified colorimetric test for point-of-care clinical diagnosis of COVID-19

M Alafeef, P Moitra, K Dighe, D Pan - Nature Protocols, 2021 - nature.com
The global pandemic of coronavirus disease 2019 (COVID-19) highlights the shortcomings
of the current testing paradigm for viral disease diagnostics. Here, we report a stepwise …

Isothermal amplifications–a comprehensive review on current methods

J Glökler, TS Lim, J Ida, M Frohme - Critical reviews in biochemistry …, 2021 - Taylor & Francis
The introduction of nucleic acid amplification techniques has revolutionized the field of
medical diagnostics in the last decade. The advent of PCR catalyzed the increasing …

An amplification-free ultra-sensitive electrochemical CRISPR/Cas biosensor for drug-resistant bacteria detection

A Suea-Ngam, PD Howes, AJ DeMello - Chemical science, 2021 - pubs.rsc.org
Continued development of high-performance and cost-effective in vitro diagnostic tools is
vital for improving infectious disease treatment and transmission control. For nucleic acid …

Isothermal nucleic acid amplification for food safety analysis

X **a, H Yang, J Cao, J Zhang, Q He, R Deng - TrAC Trends in Analytical …, 2022 - Elsevier
Rapid assays allowing for on-site or in-field testing can enable us to detect food
contamination in a timely manner, thus facilitating the insurance of food safety. Isothermal …

Machine learning and chemometrics for electrochemical sensors: moving forward to the future of analytical chemistry

P Puthongkham, S Wirojsaengthong, A Suea-Ngam - Analyst, 2021 - pubs.rsc.org
Electrochemical sensors and biosensors have been successfully used in a wide range of
applications, but systematic optimization and nonlinear relationships have been …

[HTML][HTML] LAMP-based point-of-care biosensors for rapid pathogen detection

D Das, CW Lin, HS Chuang - Biosensors, 2022 - mdpi.com
Seeking optimized infectious pathogen detection tools is of primary importance to lessen the
spread of infections, allowing prompt medical attention for the infected. Among nucleic-acid …

Microfluidic-assisted integrated nucleic acid test strips for POCT

N Wang, J Zhang, B **ao, A Chen - Talanta, 2024 - Elsevier
Numerous diseases have posed significant threats to public health, notably the global
pandemic of COVID-19, resulting in widespread devastation due to its high infectivity and …

On-site airborne pathogen detection for infection risk mitigation

G Qiu, X Zhang, AJ deMello, M Yao, J Cao… - Chemical Society …, 2023 - pubs.rsc.org
Human-infecting pathogens that transmit through the air pose a significant threat to public
health. As a prominent instance, the severe acute respiratory syndrome coronavirus 2 …

based analytical devices for virus detection: Recent strategies for current and future pandemics

T Ozer, CS Henry - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
The importance of user-friendly, inexpensive, sensitive, and selective detection of viruses
has been highlighted again due to the recent Coronavirus disease 2019 (COVID-19) …

Multivalent duplexed-aptamer networks regulated a CRISPR-Cas12a system for circulating tumor cell detection

Z Lv, Q Wang, M Yang - Analytical Chemistry, 2021 - ACS Publications
Although circulating tumor cells (CTCs) have great potential to act as the mini-invasive liquid
biopsy cancer biomarker, a rapid and sensitive CTC detection method remains lacking …