Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Abiotic stress in crop production
The vast majority of agricultural land undergoes abiotic stress that can significantly reduce
agricultural yields. Understanding the mechanisms of plant defenses against stresses and …
agricultural yields. Understanding the mechanisms of plant defenses against stresses and …
Overloaded and stressed: whole-cell considerations for bacterial synthetic biology
Highlights•Predictability and robustness are major challenges for synthetic
biology.•Engineering bacteria requires putting synthetic constructs into growing host …
biology.•Engineering bacteria requires putting synthetic constructs into growing host …
Mitochondrial ATP generation is more proteome efficient than glycolysis
Metabolic efficiency profoundly influences organismal fitness. Nonphotosynthetic organisms,
from yeast to mammals, derive usable energy primarily through glycolysis and respiration …
from yeast to mammals, derive usable energy primarily through glycolysis and respiration …
Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients
The gut microbiome has been shown to influence the response of tumors to anti–PD-1
(programmed cell death–1) immunotherapy in preclinical mouse models and observational …
(programmed cell death–1) immunotherapy in preclinical mouse models and observational …
Targeting cancer with small-molecule pan-KRAS degraders
Mutations in the Kirsten rat sarcoma viral oncogene homolog (KRAS) protein are highly
prevalent in cancer. However, small-molecule concepts that address oncogenic KRAS …
prevalent in cancer. However, small-molecule concepts that address oncogenic KRAS …
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells
The neurovascular unit (NVU) regulates metabolic homeostasis as well as drug
pharmacokinetics and pharmacodynamics in the central nervous system. Metabolic fluxes …
pharmacokinetics and pharmacodynamics in the central nervous system. Metabolic fluxes …
Stringent response ensures the timely adaptation of bacterial growth to nutrient downshift
M Zhu, X Dai - Nature Communications, 2023 - nature.com
Timely adaptation to nutrient downshift is crucial for bacteria to maintain fitness during feast
and famine cycle in the natural niche. However, the molecular mechanism that ensures the …
and famine cycle in the natural niche. However, the molecular mechanism that ensures the …
Proteomics of melanoma response to immunotherapy reveals mitochondrial dependence
Immunotherapy has revolutionized cancer treatment, yet most patients do not respond. Here,
we investigated mechanisms of response by profiling the proteome of clinical samples from …
we investigated mechanisms of response by profiling the proteome of clinical samples from …
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage
In metabolism, available free energy is limited and must be divided across pathway steps to
maintain a negative Δ G throughout. For each reaction, Δ G is log proportional both to a …
maintain a negative Δ G throughout. For each reaction, Δ G is log proportional both to a …
Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurements
Turnover numbers, also known as k cat values, are fundamental properties of enzymes.
However, k cat data are scarce and measured in vitro, thus may not faithfully represent the in …
However, k cat data are scarce and measured in vitro, thus may not faithfully represent the in …