Protein prenylation in mechanotransduction: implications for disease and therapy
H Chen, J Yang, Q Yang, Y Jia, X Guo - Trends in Pharmacological …, 2025 - cell.com
The process by which cells translate external mechanical cues into intracellular biochemical
signals involves intricate mechanisms that remain unclear. In recent years, research into …
signals involves intricate mechanisms that remain unclear. In recent years, research into …
Dentin Mechanobiology: Bridging the Gap between Architecture and Function
X Fu, HS Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
It is remarkable how teeth maintain their healthy condition under exceptionally high levels of
mechanical loading. This suggests the presence of inherent mechanical adaptation …
mechanical loading. This suggests the presence of inherent mechanical adaptation …
Biomimetic Topological Micropattern Arrays Regulate the Heterogeneity of Cellular Fates in Lung Fibroblasts between Fibrosis and Invasion
X Zhu, S Mao, Y Yang, X Liu, Q Liu, N Zhang, Y Yang… - ACS …, 2025 - ACS Publications
Idiopathic pulmonary fibrosis (IPF) is characterized by persistent tissue injury, dysregulated
wound healing, and extracellular matrix (ECM) deposition by myofibroblasts (MFs) through …
wound healing, and extracellular matrix (ECM) deposition by myofibroblasts (MFs) through …
[HTML][HTML] Dual effect of targeting LSD1 on the invasiveness and the mechanical response of acute lymphoblastic leukemia cells
R González-Novo, M Armesto… - Biomedicine & …, 2025 - Elsevier
Epigenetic alterations are hallmarks of cancer, with histone modifiers playing critical roles in
gene transcription, DNA homeostasis, and other nuclear functions. Lysine-specific …
gene transcription, DNA homeostasis, and other nuclear functions. Lysine-specific …
AURKA Activates FOXO3a to Form a Positive Feedback Loop in the Proliferation and Migration of Keloid Fibroblasts
X Chu, J Sun, S Dai, Y Liang, X Qian, J Xu… - Advances in Wound …, 2024 - liebertpub.com
Objective: Keloids are benign fibroproliferative disorders with invasive growth exceeding the
wound boundary. Aurora kinase A (AURKA) is a serine/threonine kinase highly expressed in …
wound boundary. Aurora kinase A (AURKA) is a serine/threonine kinase highly expressed in …
Human adipose mesenchymal stem cell-derived exosomes alleviate fibrosis by restraining ferroptosis in keloids
Y Tian, M Li, R Cheng, X Chen, Z Xu, J Yuan… - Frontiers in …, 2024 - frontiersin.org
Background Keloid is a fibroproliferative disease with unsatisfactory therapeutic effects and
a high recurrence rate. exosomes produced by adipose-derived mesenchymal stem cells …
a high recurrence rate. exosomes produced by adipose-derived mesenchymal stem cells …