Structural determinants of stimuli-responsiveness in amphiphilic macromolecular nano-assemblies

H Liu, HH Lu, Y Alp, R Wu, S Thayumanavan - Progress in Polymer …, 2024 - Elsevier
Stimuli-responsive nano-assemblies from amphiphilic macromolecules could undergo
controlled structural transformations and generate diverse macroscopic phenomenon under …

Amphiphilic block copolymers: From synthesis including living polymerization methods to applications in drug delivery

A Krishnan, S Roy, S Menon - European Polymer Journal, 2022 - Elsevier
Controlled radical polymerization (CRP) is a useful tool for the synthesis of new polymeric
materials with varying compositions, functionalities, and topologies capable of self-assembly …

Self-assembly of random copolymers

L Li, K Raghupathi, C Song, P Prasad… - Chemical …, 2014 - pubs.rsc.org
Self-assembly of random copolymers has attracted considerable attention recently. In this
feature article, we highlight the use of random copolymers to prepare nanostructures with …

Homopolymer self-assembly: principles, driving forces, and applications

J Li, Y Fan, Q Gu, X Zhou, H Sun, J Du - Chemistry of Materials, 2023 - ACS Publications
Homopolymer self-assembly has attracted much attention in polymer science and soft
nanomaterials due to the fuzzy boundary between hydrophilic and hydrophobic moieties of …

Doxorubicin-loaded, charge reversible, folate modified HPMA copolymer conjugates for active cancer cell targeting

L Li, Q Yang, Z Zhou, J Zhong, Y Huang - Biomaterials, 2014 - Elsevier
Although folate exhibits many advantages over other targeting ligands, it has one major
defect: poor water solubility. Once it was conjugated to hydrophilic drug carrier such as N-(2 …

Surface charge switchable polymer/DNA nanoparticles responsive to tumor extracellular ph for tumor-triggered enhanced gene delivery

YJ Ooi, Y Wen, J Zhu, X Song, J Li - Biomacromolecules, 2020 - ACS Publications
A tumor-targeted surface charge switchable polymeric gene delivery system with the
function of switching surface charge upon reaching the tumor site owing to the tumor …

A comprehensive outlook of synthetic strategies and applications of redox‐responsive nanogels in drug delivery

P Kumar, B Liu, G Behl - Macromolecular bioscience, 2019 - Wiley Online Library
Increasing recognition of the role of oxidative stress in the pathogenesis of many clinical
conditions and the existence of defined redox potential in healthy tissues has led to …

Fabrication of thermoresponsive nanogels by thermo-nanoprecipitation and in situ encapsulation of bioactives

M Giulbudagian, M Asadian-Birjand, D Steinhilber… - Polymer …, 2014 - pubs.rsc.org
A synthetic method for thermoresponsive, glycerol based nanogels has been developed.
The nanogels were synthesized by nanoprecipitation of the orthogonally functionalized …

Influence of Polymer Structure and Architecture on Drug Loading and Redox-Triggered Release

P Wu, J Gao, P Prasad, K Dutta, P Kanjilal… - …, 2021 - ACS Publications
Disulfide cross-linked nanoassemblies have attracted considerable attention as a drug
delivery vehicle due to their responsiveness to the natural redox gradient in biology …

Enzyme and thermal dual responsive amphiphilic polymer core–shell nanoparticle for doxorubicin delivery to cancer cells

S Kashyap, N Singh, B Surnar… - …, 2016 - ACS Publications
Dual responsive polymer nanoscaffolds for administering anticancer drugs both at the tumor
site and intracellular compartments are made for improving treatment in cancers. The …