Hydrazide–hydrazones possess a wide spectrum of bioactivity, including antibacterial,
antitubercular, antifungal, anticancer, anti-inflammatory, anticonvulsant, antidepressant …

Thiazole derivatives remains honored heterocycles in the field of medicinal chemistry. This
scaffold has been proven as a universal motif that is present in numerous pharmacologically …

The human gastrointestinal (GI) tract harbors diverse microbes, and the family
Lachnospiraceae is one of the most abundant and widely occurring bacterial groups in the …

Tuberculosis, an infectious disease, has been reported to cause the death of 1.5 million in
2018. Due to the emergence of Multi-Drug Resistant-TB, Extensively Drug Resistant-TB, and …

Today, tuberculosis (TB) caused by the acid-fast bacilli, Mycobacterium tuberculosis (Mtb) is
the most infectious killer disease globally with high morbidity and mortality rates. The rapid …

Joining the global fight against Tuberculosis, the world's most deadly infectious disease,
herein we present the design and synthesis of novel isatin-nicotinohydrazide hybrids (5a–m …

To discover anticancer drugs with novel structures and expand our research scope,
pyrazoline derivatives (3a–3l) were designed and synthesized through cyclization of …

Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …

The Lachnospiraceae is a family of anaerobic bacteria in the class Clostridia with potential
to advance the bio-economy and intestinal therapeutics. Some species of Lachnospiraceae …

Tuberculosis is an extremely serious problem of global public health. Its incidence is
worsened by the presence of multidrug-resistant (MDR) strains of Mycobacterium …