Large-conductance Ca2+-and voltage-activated K+ (BK) channels play many physiological
roles ranging from the maintenance of smooth muscle tone to hearing and neurosecretion …

Alternative splicing of pre-messenger RNA and reversible protein phosphorylation are
fundamental mechanisms for regulating protein structure and function. Recent studies of one …

Tolerance represents a critical component of addiction. The large-conductance calcium-and
voltage-activated potassium channel (BK) is a well-established alcohol target, and an …

The pore-forming α-subunits of large conductance calcium-and voltage-activated potassium
(BK) channels are encoded by a single gene that undergoes extensive alternative pre …

Homeostasis of neural firing properties is important in stabilizing neuronal circuitry, but how
such plasticity might depend on alternative splicing is not known. Here we report that chronic …

Abstract Large‐conductance Ca2+‐activated K+ (BKCa) channels are activated by
membrane depolarization and modulated by intracellular Ca2+. Here, we report the direct …

Evidence that Ca2+-activated K+ (KCa) channels play a role in cell volume changes and K+
homeostasis led to a prediction that astrocytes would have KCa channels near blood …

Large-conductance voltage-and calcium-sensitive channels are known to be expressed in
the plasmalemma of central neurons; however, recent data suggest that large-conductance …

We investigated the expression of splice variants and β-subunits of the BK channel (big
conductance Ca2+-activated K+ channel, Slo1, MaxiK, KCa1. 1) in rat cerebral blood …

Molecular diversity of ion channel structure and function underlies variability in electrical
signaling in nerve, muscle, and non-excitable cells. Protein phosphorylation and alternative …