Pesticide exposure and the microbiota-gut-brain axis

R Matsuzaki, E Gunnigle, V Geissen, G Clarke… - The ISME …, 2023 - academic.oup.com
The gut microbiota exist within a dynamic ecosystem shaped by various factors that includes
exposure to xenobiotics such as pesticides. It is widely regarded that the gut microbiota …

[HTML][HTML] Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation

F Liu, Y Wang, L Chen, BK Bello, T Zhang… - Ecotoxicology and …, 2022 - Elsevier
Excessive use of hard-to-degrade pesticides threatens the ecological health of aquatic
systems. This study aimed to investigate difenoconazole (DFZ) residues in the environment …

Zinc nanoparticles ameliorate oxidative stress and apoptosis induced by silver nanoparticles in the brain of male rats

PA Noshy, NAE Yasin, MM Rashad, AM Shehata… - Neurotoxicology, 2023 - Elsevier
The current study was conducted to investigate the possible ameliorative role of zinc
nanoparticles (Zn NPs) against silver nanoparticles (Ag NPs)-induced oxidative and …

Ceratonia siliqua pods (Carob) methanol extract alleviates doxorubicin-induced nephrotoxicity via antioxidant, anti-inflammatory and anti-apoptotic pathways in rats

AH Atta, SA Atta, MS Khattab, THA El-Aziz… - … Science and Pollution …, 2023 - Springer
Doxorubicin (DOX) is an anti-neoplastic therapy, but its use is limited by its deleterious toxic
effects including nephrotoxicity and cardiotoxicity. This work aimed at assessing the …

[HTML][HTML] Origanum majorana essential oil improves the rat's sexual behavior and testicular oxidative damage induced by imidacloprid via modulating the …

S Mehanna, MY Issa, NH Hassan, AM Hussien… - Saudi Pharmaceutical …, 2022 - Elsevier
The neonicotinoid insecticide imidacloprid has been linked to significant reproductive
damage in mammals. Origanum majorana essential oil (OME) is a natural herbal product …

Comparative assessment on the probable mechanisms underlying the hepatorenal toxicity of commercial imidacloprid and hexaflumuron formulations in rats

EI Hassanen, AM Hussien, S Mehanna… - … Science and Pollution …, 2022 - Springer
Pesticides are viewed as a major wellspring of ecological contamination and causing
serious risky consequences for people and animals. Imidacloprid (IM) and hexaflumuron …

Impact of buffered sodium butyrate as a partial or total dietary alternative to lincomycin on performance, IGF-1 and TLR4 genes expression, serum indices, intestinal …

BM Bawish, MFS Zahran, E Ismael, S Kamel… - Acta Veterinaria …, 2023 - Springer
Background Sodium butyrate (SB) is a short-chain fatty acid and a safe antibiotic alternative.
During 35 days, this study compared the impact of coated SB (Butirex C4) and lincomycin …

The potential mechanism underlying the hepatorenal toxicity induced by hymexazol in rats and the role of NF‐κB signaling pathway

NH Hassan, S Mehanna, AM Hussien… - … of Biochemical and …, 2023 - Wiley Online Library
Hymexazol (HML) is widely used in agriculture as a systemic fungicide and plant growth
promoter. Humans are continuously exposed to HML via various routes. The liver and …

[HTML][HTML] Resveratrol ameliorates penconazole-induced cardiotoxicity by inhibition of oxidative stress and apoptosis in zebrafish larvae

X Jiang, J Wang, J Liu, H Zhu, J Hu, X Sun… - … and Environmental Safety, 2023 - Elsevier
Penconazole (PEN) is a typical systemic triazole fungicide with cardiac toxic effects.
Resveratrol (RES) is a natural polyphenolic phytochemical with antioxidation properties …

Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways

EI Hassanen, HA Mansour, MY Issa, MA Ibrahim… - Food and Chemical …, 2024 - Elsevier
Ingestion of prominent levels of histamine (HIS) leads to dangerous effects on biological
systems. The most frequent and active catechin in green tea is epigallocatechin gallate …