Kaposi sarcoma

E Cesarman, B Damania, SE Krown, J Martin… - Nature reviews Disease …, 2019 - nature.com
Kaposi sarcoma (KS) gained public attention as an AIDS-defining malignancy; its
appearance on the skin was a highly stigmatizing sign of HIV infection during the height of …

Castleman disease

A Carbone, M Borok, B Damania, A Gloghini… - Nature Reviews …, 2021 - nature.com
Castleman disease (CD), a heterogeneous group of disorders that share morphological
features, is divided into unicentric CD and multicentric CD (MCD) according to the clinical …

HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus

KA Lurain, R Ramaswami, LT Krug… - Clinical Microbiology …, 2024 - journals.asm.org
Within weeks of the first report of acquired immunodeficiency syndrome (AIDS) in 1981, it
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …

KSHV/HHV8-mediated hematologic diseases

E Cesarman, A Chadburn… - Blood, The Journal of …, 2022 - ashpublications.org
Kaposi sarcoma (KS) herpesvirus (KSHV), also known as human herpesvirus 8, is the
causal agent of KS but is also pathogenetically related to several lymphoproliferative …

Viral oncology: molecular biology and pathogenesis

UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

Virus-like particles as preventive and therapeutic cancer vaccines

AL Tornesello, M Tagliamonte, FM Buonaguro… - Vaccines, 2022 - mdpi.com
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …

Diagnosis and treatment of Kaposi's sarcoma: European consensus-based interdisciplinary guideline (EDF/EADO/EORTC)

C Lebbe, C Garbe, AJ Stratigos, C Harwood… - European Journal of …, 2019 - Elsevier
Kaposi's sarcoma (KS) is a multifocal neoplasm of lymphatic endothelium-derived cells
infected with human herpesvirus 8. Four clinical subtypes are distinguished: the classic, the …

Diagnosis and treatment of Kaposi sarcoma

JW Schneider, DP Dittmer - American journal of clinical dermatology, 2017 - Springer
Kaposi sarcoma (KS) is the most common neoplasm of people living with HIV today. In Sub-
Saharan Africa, KS is among the most common cancers in men, overall. Not only HIV …

Microbiota dysbiosis in select human cancers: evidence of association and causality

J Chen, JC Domingue, CL Sears - Seminars in immunology, 2017 - Elsevier
The human microbiota is a complex ecosystem of diverse microorganisms consisting of
bacteria, viruses, and fungi residing predominantly in epidermal and mucosal habitats …

KSHV (HHV8) vaccine: promises and potential pitfalls for a new anti-cancer vaccine

C Casper, L Corey, JI Cohen, B Damania, AA Gershon… - npj Vaccines, 2022 - nature.com
Seven viruses cause at least 15% of the total cancer burden. Viral cancers have been
described as the “low-hanging fruit” that can be potentially prevented or treated by new …