Abstract Context Prostate cancer (PCa) is one of the most common cancers worldwide.
Understanding the epidemiology and risk factors of the disease is paramount to improve …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well recognized for
playing a dual role, since they can be either deleterious or beneficial to biological systems …

Cellular redox homeostasis is an essential, dynamic process that ensures the balance
between reducing and oxidizing reactions within cells and thus has implications across all …

Selenium is a trace mineral that is essential for health. After being obtained from food and
taken up by the liver, selenium performs various physiological functions in the body in the …

Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …

Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …

Importance Obesity, defined as a body mass index (BMI) greater than 30, is associated with
a significant increase in the risk of many cancers and in overall mortality. However, various …

Reactive oxygen species (ROS) play important roles in tissue homeostasis, cellular
signaling, differentiation, and survival. In this review, we discuss the types of ROS, their …

This review addresses the role of the essential trace element, selenium, in type-2 diabetes
mellitus (T2DM) and its metabolic co-morbidities, ie, metabolic syndrome, obesity and non …

Importance Cardiovascular disease and cancer are the 2 leading causes of death in the US,
and vitamin and mineral supplementation has been proposed to help prevent these …