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Advances in microfluidic PCR for point-of-care infectious disease diagnostics
Global burdens from existing or emerging infectious diseases emphasize the need for point-
of-care (POC) diagnostics to enhance timely recognition and intervention. Molecular …
of-care (POC) diagnostics to enhance timely recognition and intervention. Molecular …
Diagnosis of bloodstream infections: an evolution of technologies towards accurate and rapid identification and antibiotic susceptibility testing
Bloodstream infections (BSI) are a leading cause of death worldwide. The lack of timely and
reliable diagnostic practices is an ongoing issue for managing BSI. The current gold …
reliable diagnostic practices is an ongoing issue for managing BSI. The current gold …
[HTML][HTML] Next-generation molecular diagnostics: Leveraging digital technologies to enhance multiplexing in real-time PCR
Real-time polymerase chain reaction (qPCR) enables accurate detection and quantification
of nucleic acids and has become a fundamental tool in biological sciences, bioengineering …
of nucleic acids and has become a fundamental tool in biological sciences, bioengineering …
Catheterization alters bladder ecology to potentiate Staphylococcus aureus infection of the urinary tract
JN Walker, AL Flores-Mireles, CL Pinkner… - Proceedings of the …, 2017 - pnas.org
Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging cause of catheter-
associated urinary tract infection (CAUTI), which frequently progresses to more serious …
associated urinary tract infection (CAUTI), which frequently progresses to more serious …
High-resolution DNA melting analysis in clinical research and diagnostics
Among nucleic acid analytical methods, high-resolution melting analysis is gaining more
and more attention. High-resolution melting provides simple, homogeneous solutions for …
and more attention. High-resolution melting provides simple, homogeneous solutions for …
Microbiological applications of high-resolution melting analysis
High-resolution melting (HRM) analysis uses real-time PCR instrumentation to interrogate
DNA sequence variation and is a low-cost, single-step, closed-tube method. Here we …
DNA sequence variation and is a low-cost, single-step, closed-tube method. Here we …
Targeted treatment for bacterial infections: prospects for pathogen-specific antibiotics coupled with rapid diagnostics
The advent of antibiotics in the early twentieth century catalyzed a medical revolution,
drastically reducing mortality due to bacterial infections. Along with numerous other …
drastically reducing mortality due to bacterial infections. Along with numerous other …
Nanoarray digital polymerase chain reaction with high-resolution melt for enabling broad bacteria identification and pheno–molecular antimicrobial susceptibility test
Toward combating infectious diseases caused by pathogenic bacteria, there remains an
unmet need for diagnostic tools that can broadly identify the causative bacteria and …
unmet need for diagnostic tools that can broadly identify the causative bacteria and …
Integrated bacterial identification and antimicrobial susceptibility testing using PCR and high-resolution melt
Accurate and timely diagnostics are critical for managing bacterial infections. The current
gold standard, culture-based diagnostics, can provide clinicians with comprehensive …
gold standard, culture-based diagnostics, can provide clinicians with comprehensive …
Emerging analytical techniques for rapid pathogen identification and susceptibility testing
In the face of looming threats from multi-drug resistant microorganisms, there is a growing
need for technologies that will enable rapid identification and drug susceptibility profiling of …
need for technologies that will enable rapid identification and drug susceptibility profiling of …