Optimal transport for single-cell and spatial omics
High-throughput single-cell profiling provides an unprecedented ability to uncover the
molecular states of millions of cells. These technologies are, however, destructive to cells …
molecular states of millions of cells. These technologies are, however, destructive to cells …
Perteval-scfm: Benchmarking single-cell foundation models for perturbation effect prediction
In silico modeling of transcriptional responses to perturbations is crucial for advancing our
understanding of cellular processes and disease mechanisms. We present PertEval-scFM, a …
understanding of cellular processes and disease mechanisms. We present PertEval-scFM, a …
Transcriptome-wide characterization of genetic perturbations
Single cell CRISPR screens such as Perturb-seq enable transcriptomic profiling of genetic
perturbations at scale. However, the data produced by these screens are often noisy due to …
perturbations at scale. However, the data produced by these screens are often noisy due to …