Experimental models of brain ischemia: a review of techniques, magnetic resonance imaging, and investigational cell-based therapies
A Canazza, L Minati, C Boffano, E Parati… - Frontiers in …, 2014 - frontiersin.org
Stroke continues to be a significant cause of death and disability worldwide. Although major
advances have been made in the past decades in prevention, treatment, and rehabilitation …
advances have been made in the past decades in prevention, treatment, and rehabilitation …
Distal occlusion of the middle cerebral artery in mice: are we ready to assess long-term functional outcome?
Rodent animal models of stroke are widely used with brain ischemia inducible by various
occlusion methods. Permanent or transient occlusion of the distal portion of the middle …
occlusion methods. Permanent or transient occlusion of the distal portion of the middle …
Single severe traumatic brain injury produces progressive pathology with ongoing contralateral white matter damage one year after injury
There is increasing recognition that traumatic brain injury (TBI) may initiate long-term
neurodegenerative processes, particularly chronic traumatic encephalopathy. However …
neurodegenerative processes, particularly chronic traumatic encephalopathy. However …
Treatment of ischemic stroke by atorvastatin-loaded PEGylated liposome
There is insufficient evidence on the effect of nanoparticles, particularly liposomes loaded
with a statin, on acute ischemic stroke. We investigated the impact of atorvastatin-loaded …
with a statin, on acute ischemic stroke. We investigated the impact of atorvastatin-loaded …
Ceruloplasmin plays a neuroprotective role in cerebral ischemia
Ceruloplasmin (Cp) is a ferroxidase that also plays a role in iron efflux from cells. It can thus
help to regulate cellular iron homeostasis. In the CNS, Cp is expressed as a membrane …
help to regulate cellular iron homeostasis. In the CNS, Cp is expressed as a membrane …
Circulating extracellular vesicles promote recovery in a preclinical model of intracerebral hemorrhage
F Laso-García, L Casado-Fernández, D Piniella… - … Therapy-Nucleic Acids, 2023 - cell.com
Circulating extracellular vesicles (EVs) are proposed to participate in enhancing pathways of
recovery after stroke through paracrine signaling. To verify this hypothesis in a proof-of …
recovery after stroke through paracrine signaling. To verify this hypothesis in a proof-of …
Iron overload, measured as serum ferritin, increases brain damage induced by focal ischemia and early reperfusion
I García-Yébenes, M Sobrado, A Moraga… - Neurochemistry …, 2012 - Elsevier
High levels of iron, measured as serum ferritin, are associated to a worse outcome after
stroke. However, it is not known whether ischemic damage might increase ferritin levels as …
stroke. However, it is not known whether ischemic damage might increase ferritin levels as …
Beneficial potential of intravenously administered IL-6 in improving outcome after murine experimental stroke
MH Grønhøj, BH Clausen, CD Fenger… - Brain, behavior, and …, 2017 - Elsevier
Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine with neuroprotective properties. Still, the
therapeutic potential of IL-6 after experimental stroke has not yet been investigated in a …
therapeutic potential of IL-6 after experimental stroke has not yet been investigated in a …
[HTML][HTML] Advancing post-stroke depression research: insights from murine models and behavioral analyses
Post-stroke depression (PSD) represents a significant neuropsychiatric complication that
affects between 39% and 52% of stroke survivors, leading to impaired recovery, decreased …
affects between 39% and 52% of stroke survivors, leading to impaired recovery, decreased …
Tannic acid protects aged brain against cerebral hypoperfusion via modulation of Nrf2 and inflammatory pathways
Current study purposed to investigate the neuroprotective effects of Tannic Acid (TA) on mild
chronic cerebral hypoperfusion model in rats. Male Wistar rats were subjected to permanent …
chronic cerebral hypoperfusion model in rats. Male Wistar rats were subjected to permanent …