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Multisystem physiological perspective of human frailty and its modulation by physical activity
“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …
Association of age and sex with multi-modal cerebral physiology in adult moderate/severe traumatic brain injury: a narrative overview and future avenues for …
The impact of age and biological sex on outcome in moderate/severe traumatic brain injury
(TBI) has been documented in large cohort studies, with advanced age and male sex linked …
(TBI) has been documented in large cohort studies, with advanced age and male sex linked …
[HTML][HTML] Age and sex related differences in orthostatic cerebral oxygenation: Findings from 2764 older adults in the Irish Longitudinal Study on Ageing (TILDA)
Aims Cerebral hypoperfusion is implicated in the pathogenesis of associations between
orthostatic hypotension and adverse outcome such as falls, cognitive impairment …
orthostatic hypotension and adverse outcome such as falls, cognitive impairment …
Associations between neurocardiovascular signal entropy and physical frailty
In this cross-sectional study, the relationship between noninvasively measured
neurocardiovascular signal entropy and physical frailty was explored in a sample of …
neurocardiovascular signal entropy and physical frailty was explored in a sample of …
Carbon dioxide and cardiac output as major contributors to cerebral oxygenation during apnoeic oxygenation
Apnoeic oxygenation has experienced a resurgence in interest in critical care and
perioperative medicine. However, its effect on cerebral oxygenation and factors influencing …
perioperative medicine. However, its effect on cerebral oxygenation and factors influencing …
Applying systems thinking to unravel the mechanisms underlying orthostatic hypotension related fall risk
L Wang, AC Pronk, EP van Poelgeest, R Briggs… - Geroscience, 2023 - Springer
Orthostatic hypotension (OH) is an established and common cardiovascular risk factor for
falls. An in-depth understanding of the various interacting pathophysiological pathways …
falls. An in-depth understanding of the various interacting pathophysiological pathways …
The Impact of Type 2 Diabetes on Peripheral and Cerebral Hemodynamic Responses to Active Stand
Background Although type 2 diabetes mellitus (T2DM) is an established risk factor for
cognitive impairment, the underlying mechanisms remain poorly explored. One potential …
cognitive impairment, the underlying mechanisms remain poorly explored. One potential …
Influences of sex chromosome aneuploidy on height, weight, and body mass index in human childhood and adolescence
C Hanson, J Blumenthal, L Clasen… - American Journal of …, 2024 - Wiley Online Library
Sex chromosome aneuploidies (SCAs) are collectively common conditions caused by
carriage of a sex chromosome dosage other than XX for females and XY for males …
carriage of a sex chromosome dosage other than XX for females and XY for males …
Hemodynamic and structural brain measures in high and low sedentary older adults
Due to its cardiovascular effects sedentary behaviour might impact cerebrovascular function
in the long term, affecting cerebrovascular regulatory mechanisms and perfusion levels …
in the long term, affecting cerebrovascular regulatory mechanisms and perfusion levels …
Were Frailty Identification Criteria Created Equal? A Comparative Case Study on Continuous Non-Invasively Collected Neurocardiovascular Signals during an Active …
Background: In this observational study, we compared continuous physiological signals
during an active standing test in adults aged 50 years and over, characterised as frail by …
during an active standing test in adults aged 50 years and over, characterised as frail by …