Local cancer recurrence: the realities, challenges, and opportunities for new therapies

DA Mahvi, R Liu, MW Grinstaff… - CA: a cancer journal …, 2018 - Wiley Online Library
Locoregional recurrence negatively impacts both long‐term survival and quality of life for
several malignancies. For appropriate‐risk patients with an isolated, resectable, local …

Curcumin in cancer therapy: A novel adjunct for combination chemotherapy with paclitaxel and alleviation of its adverse effects

M Ashrafizadeh, A Zarrabi, F Hashemi, ER Moghadam… - Life sciences, 2020 - Elsevier
Dealing with cancer is of importance due to enhanced incidence rate of this life-threatening
disorder. Chemotherapy is an ideal candidate in overcoming and eradication of cancer. To …

Nanomedicine applications in the treatment of breast cancer: current state of the art

D Wu, M Si, HY Xue, HL Wong - International journal of …, 2017 - Taylor & Francis
Breast cancer is the most common malignant disease in women worldwide, but the current
drug therapy is far from optimal as indicated by the high death rate of breast cancer patients …

Recent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy

E Piktel, K Niemirowicz, M Wątek, T Wollny… - Journal of …, 2016 - Springer
The rapid development of nanotechnology provides alternative approaches to overcome
several limitations of conventional anti-cancer therapy. Drug targeting using functionalized …

Anticancer and cardio-protective effects of liposomal doxorubicin in the treatment of breast cancer

YL Franco, TR Vaidya, S Ait-Oudhia - Breast Cancer: Targets and …, 2018 - Taylor & Francis
Breast cancer (BC) is a highly prevalent disease, accounting for the second highest number
of cancer-related mortalities worldwide. The anthracycline doxorubicin (DOX), isolated from …

New insights and evolving role of pegylated liposomal doxorubicin in cancer therapy

AA Gabizon, Y Patil, NM La-Beck - Drug resistance updates, 2016 - Elsevier
We herein review various pharmacological and clinical aspects of pegylated liposomal
doxorubicin (PLD), the first nanomedicine to be approved for cancer therapy, and discuss …

Application of chitosan modified nanocarriers in breast cancer

SK Dubey, T Bhatt, M Agrawal, RN Saha… - International Journal of …, 2022 - Elsevier
As per the WHO, every year around 2.1 million women are detected with breast cancer. It is
one of the most invasive cancer in women and second most among all, contributing around …

pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects

LJC Albuquerque, V Sincari, A Jäger, J Kucka… - Journal of Controlled …, 2021 - Elsevier
The delivery of therapeutics into sites of action by using cargo-delivery platforms potentially
minimizes their premature degradation and fast clearance from the bloodstream …

Current status of nanomedicine in the chemotherapy of breast cancer

AI Fraguas-Sánchez, C Martín-Sabroso… - Cancer chemotherapy …, 2019 - Springer
Despite the efforts that have been made in the field of breast cancer therapy, it is a leading
cause of cancer death in women and a major health problem. The current treatments …

A comprehensive review on doxorubicin: mechanisms, toxicity, clinical trials, combination therapies and nanoformulations in breast cancer

A Bisht, D Avinash, KK Sahu, P Patel… - Drug Delivery and …, 2024 - Springer
Doxorubicin is a key treatment for breast cancer, but its effectiveness often comes with
significant side effects. Its actions include DNA intercalation, topoisomerase II inhibition, and …