Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022‏ - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021‏ - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

Cognitive motor dissociation in disorders of consciousness

YG Bodien, J Allanson, P Cardone… - … England Journal of …, 2024‏ - Mass Medical Soc
Background Patients with brain injury who are unresponsive to commands may perform
cognitive tasks that are detected on functional magnetic resonance imaging (fMRI) and …

A manual for the glasgow outcome scale-extended interview

L Wilson, K Boase, LD Nelson, NR Temkin… - Journal of …, 2021‏ - liebertpub.com
The Glasgow Outcome Scale-Extended (GOSE) has become one of the most widely used
outcome instruments to assess global disability and recovery after traumatic brain injury …

Electroencephalogram in the intensive care unit: a focused look at acute brain injury

A Alkhachroum, B Appavu, S Egawa, B Foreman… - Intensive care …, 2022‏ - Springer
Over the past decades, electroencephalography (EEG) has become a widely applied and
highly sophisticated brain monitoring tool in a variety of intensive care unit (ICU) settings …

Preservation of brain activity in unresponsive patients identifies MCS star

A Thibaut, R Panda, J Annen, LRD Sanz… - Annals of …, 2021‏ - Wiley Online Library
Objective Brain‐injured patients who are unresponsive at the bedside (ie, vegetative
state/unresponsive wakefulness syndrome–VS/UWS) may present brain activity similar to …

Clinical and advanced neurophysiology in the prognostic and diagnostic evaluation of disorders of consciousness: review of an IFCN-endorsed expert group

A Comanducci, M Boly, J Claassen, M De Lucia… - Clinical …, 2020‏ - Elsevier
The analysis of spontaneous EEG activity and evoked potentials is a cornerstone of the
instrumental evaluation of patients with disorders of consciousness (DoC). The past few …

Consciousness and complexity: a consilience of evidence

S Sarasso, AG Casali, S Casarotto… - Neuroscience of …, 2021‏ - academic.oup.com
Over the last years, a surge of empirical studies converged on complexity-related measures
as reliable markers of consciousness across many different conditions, such as sleep …

Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions

BL Edlow, LRD Sanz, L Polizzotto, N Pouratian… - Neurocritical care, 2021‏ - Springer
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …

The neuroethics of disorders of consciousness: a brief history of evolving ideas

MJ Young, YG Bodien, JT Giacino, JJ Fins, RD Truog… - Brain, 2021‏ - academic.oup.com
Neuroethical questions raised by recent advances in the diagnosis and treatment of
disorders of consciousness are rapidly expanding, increasingly relevant and yet …