Fusion of enveloped viruses in endosomes

JM White, GR Whittaker - Traffic, 2016 - Wiley Online Library
Ari Helenius launched the field of enveloped virus fusion in endosomes with a seminal
paper in the Journal of Cell Biology in 1980. In the intervening years, a great deal has been …

[HTML][HTML] Molecular and cellular aspects of rhabdovirus entry

AAV Albertini, E Baquero, A Ferlin, Y Gaudin - Viruses, 2012 - mdpi.com
Rhabdoviruses enter the cell via the endocytic pathway and subsequently fuse with a
cellular membrane within the acidic environment of the endosome. Both receptor recognition …

Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines

MA Whitt - Journal of virological methods, 2010 - Elsevier
Vesicular stomatitis virus (VSV) is a prototypic enveloped animal virus that has been used
extensively to study virus entry, replication and assembly due to its broad host range and …

Stepwise Priming by Acidic pH and a High K+ Concentration Is Required for Efficient Uncoating of Influenza A Virus Cores after Penetration

S Stauffer, Y Feng, F Nebioglu, R Heilig… - Journal of …, 2014 - journals.asm.org
Influenza A virus (IAV) uses the low pH in late endocytic vacuoles as a cue for penetration by
membrane fusion. Here, we analyzed the prefusion reactions that prepare the core for …

Molecular determinants and dynamics of hepatitis C virus secretion

KE Coller, NS Heaton, KL Berger, JD Cooper… - PLoS …, 2012 - journals.plos.org
The current model of hepatitis C virus (HCV) production involves the assembly of virions on
or near the surface of lipid droplets, envelopment at the ER in association with components …

Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus

CE Mire, JB Geisbert, A Marzi, KN Agans… - PLoS neglected …, 2013 - journals.plos.org
Ebola virus (EBOV) causes severe and often fatal hemorrhagic fever in humans and
nonhuman primates (NHPs). Currently, there are no licensed vaccines or therapeutics for …

[HTML][HTML] Vesicular Stomatitis Virus: Insights into Pathogenesis, Immune Evasion, and Technological Innovations in Oncolytic and Vaccine Development

MM Ahmed, OJ Okesanya, BM Ukoaka, AM Ibrahim… - Viruses, 2024 - mdpi.com
Vesicular stomatitis virus (VSV) represents a significant advancement in therapeutic
medicine, offering unique molecular and cellular characteristics that make it exceptionally …

Recoding of the vesicular stomatitis virus L gene by computer-aided design provides a live, attenuated vaccine candidate

B Wang, C Yang, G Tekes, S Mueller, A Paul… - MBio, 2015 - journals.asm.org
Codon pair bias (CPB), which has been observed in all organisms, is a neglected genomic
phenomenon that affects gene expression. CPB results from synonymous codons that are …

A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating

CE Mire, JM White, MA Whitt - PLoS pathogens, 2010 - journals.plos.org
To study VSV entry and the fate of incoming matrix (M) protein during virus uncoating we
used recombinant viruses encoding M proteins with a C-terminal tetracysteine tag that could …

Labeling of multiple HIV-1 proteins with the biarsenical-tetracysteine system

CF Pereira, PC Ellenberg, KL Jones, TL Fernandez… - PloS one, 2011 - journals.plos.org
Due to its small size and versatility, the biarsenical-tetracysteine system is an attractive way
to label viral proteins for live cell imaging. This study describes the genetic labeling of the …