The CAM model—Q&A with experts

D Fischer, G Fluegen, P Garcia… - Cancers, 2022 - mdpi.com
Simple Summary The chorioallantoic membrane (CAM) model is an alternative in vivo test
system for the study of hallmarks of cancer such as angiogenesis, tumor growth, immune …

Hypoxia: syndicating triple negative breast cancer against various therapeutic regimens

N Srivastava, SS Usmani, R Subbarayan… - Frontiers in …, 2023 - frontiersin.org
Triple-negative breast cancer (TNBC) is one of the deadliest subtypes of breast cancer (BC)
for its high aggressiveness, heterogeneity, and hypoxic nature. Based on biological and …

Preclinical and clinical trials of new treatment strategies targeting cancer stem cells in subtypes of breast cancer

N Landeros, I Castillo, R Pérez-Castro - Cells, 2023 - mdpi.com
Breast cancer (BC) can be classified into various histological subtypes, each associated with
different prognoses and treatment options, including surgery, radiation, chemotherapy, and …

Nerve growth factor inducible (VGF) is a secreted mediator for metastatic breast cancer tropism to the brain

R Carvalho, L Santos, I Conde, R Leitão… - The Journal of …, 2024 - Wiley Online Library
Brain metastases are one of the most serious clinical problems in breast cancer (BC)
progression, associated with lower survival rates and a lack of effective therapies. Thus, to …

Breast cancer stem cell membrane biomarkers: therapy targeting and clinical implications

I Conde, AS Ribeiro, J Paredes - Cells, 2022 - mdpi.com
Breast cancer is the most common malignancy affecting women worldwide. Importantly,
there have been significant improvements in prevention, early diagnosis, and treatment …

The chick chorioallantoic membrane model: a new in vivo tool to evaluate breast cancer stem cell activity

MT Pinto, AS Ribeiro, I Conde, R Carvalho… - International Journal of …, 2020 - mdpi.com
The high plasticity of cancer stem-like cells (CSCs) allows them to differentiate and
proliferate, specifically when xenotransplanted subcutaneously into immunocompromised …

The chorioallantoic membrane xenograft assay as a reliable model for investigating the biology of breast cancer

RA Ranjan, JK Muenzner, P Kunze, CI Geppert… - Cancers, 2023 - mdpi.com
Simple Summary The chorioallantoic membrane (CAM) is a highly vascularized membrane
found in avian eggs. Tumor cell lines can be grown on the CAM, which allows for the further …

Breast cancer classification based on tumor budding and stem cell-related signatures facilitate prognosis evaluation

Z **ang, Q He, L Huang, B **ong, Q **ang - Frontiers in Oncology, 2022 - frontiersin.org
Background Tumor budding (TB) is emerging as a prognostic factor in multiple cancers.
Likewise, the stemness of cancer cells also plays a vital role in cancer progression …

[HTML][HTML] Current Evidence in the Systemic Treatment of Brain Metastases from Breast Cancer and Future Perspectives on New Drugs, Combinations and …

O Garrone, F Ruatta, CG Rea, N Denaro, M Ghidini… - Cancers, 2024 - mdpi.com
Breast cancer is the most frequently diagnosed neoplasm all over the world and the second
leading cause of cancer death in women. Breast cancer prognosis has significantly …

Biological characteristics of a sub-population of cancer stem cells from two triple-negative breast tumour cell lines

J Enciso-Benavides, L Alfaro, C Castañeda-Altamirano… - Heliyon, 2021 - cell.com
Triple-negative breast tumours (TNBTs) make up 15–20% of all breast tumours. There is no
treatment for them, and the role that cancer stem cells (CSCs) have in carcinogenesis is still …