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Nutritional activities of luteolin in obesity and associated metabolic diseases: an eye on adipose tissues
Z Zhang, J Wang, Y Lin, J Chen, J Liu… - Critical Reviews in Food …, 2024 - Taylor & Francis
Obesity is characterized by excessive body fat accumulation and is a high-risk factor for
metabolic comorbidities, including type 2 diabetes, nonalcoholic fatty liver disease, and …
metabolic comorbidities, including type 2 diabetes, nonalcoholic fatty liver disease, and …
Genetics, genomics, and diet interactions in obesity in the Latin American environment
Obesity is a chronic disease characterized by abnormal or excessive fat accumulation that
could impact an individual's health; moreover, the World Health Organization (WHO) has …
could impact an individual's health; moreover, the World Health Organization (WHO) has …
[HTML][HTML] Evaluation of the pharmacokinetics, chylomicron inhibition, and toxicity of colchicine in rats given low doses
Colchicine (COL) is known for its ability to inhibit the formation of intestinal chylomicrons and
has been utilized as a non-surgical tool to explore drug absorption via the intestinal …
has been utilized as a non-surgical tool to explore drug absorption via the intestinal …
Acetaminophen-induced hepatotoxicity in obesity and nonalcoholic fatty liver disease: a critical review
K Begriche, C Penhoat, P Bernabeu-Gentey, J Massart… - Livers, 2023 - mdpi.com
The epidemic of obesity, type 2 diabetes and nonalcoholic liver disease (NAFLD) favors
drug consumption, which augments the risk of adverse events including liver injury. For …
drug consumption, which augments the risk of adverse events including liver injury. For …
Pharmacokinetics of cycloheximide in rats and evaluation of its effect as a blocker of intestinal lymph formation
Cycloheximide (CHX) has been used to reduce the flow of intestinal lymph and as a non-
surgical tool to study drug absorption via the intestinal lymphatics. Pharmacokinetic …
surgical tool to study drug absorption via the intestinal lymphatics. Pharmacokinetic …
[HTML][HTML] The effect of maternal high-fat or high-carbohydrate diet during pregnancy and lactation on cytochrome P450 2D (CYP2D) in the liver and brain of rat offspring
W Kuban, A Haduch, E Bromek… - International Journal of …, 2024 - mdpi.com
Cytochrome P450 2D (CYP2D) is important in psychopharmacology as it is engaged in the
metabolism of drugs, neurosteroids and neurotransmitters. An unbalanced maternal diet …
metabolism of drugs, neurosteroids and neurotransmitters. An unbalanced maternal diet …
Maternal-placental-fetal drug metabolism is altered by late gestation undernutrition in the pregnant ewe
Background Maternal undernutrition during pregnancy disrupts both fetal growth and
development with perturbations to certain physiological processes within the maternal-fetal …
development with perturbations to certain physiological processes within the maternal-fetal …
Is platelet responsiveness to clopidogrel attenuated in overweight or obese patients and why? A reverse translational study in mice
LP Jiang, JZ Ji, PX Ge, T Zhu, QY Mi… - British Journal of …, 2022 - Wiley Online Library
Background and Purpose Overweight or obese patients exhibit poorer platelet responses to
clopidogrel. However, the mechanisms behind this phenotype remain to be elucidated …
clopidogrel. However, the mechanisms behind this phenotype remain to be elucidated …
Obesity-related genomic instability and altered xenobiotic metabolism: possible consequences for cancer risk and chemotherapy
EE Bankoglu, H Stopper - Expert Reviews in Molecular Medicine, 2022 - cambridge.org
The increase in the prevalence of obesity has led to an elevated risk for several associated
diseases including cancer. Several studies have investigated the DNA damage in human …
diseases including cancer. Several studies have investigated the DNA damage in human …
Hepatic cytochrome P450 function is reduced by life-long Western diet consumption in guinea pig independent of birth weight
Introduction Non-alcoholic fatty liver disease (NAFLD) is characterised by accumulation of
triglycerides and cholesterol within the liver and dysregulation of specific hepatic …
triglycerides and cholesterol within the liver and dysregulation of specific hepatic …