Thiazolidine-2, 4-dione derivatives as potential α-glucosidase inhibitors: synthesis, inhibitory activity, binding interaction and hypoglycemic activity

M Li, J Sun, B Liang, X Min, J Hu, R Wu, X Xu - Bioorganic Chemistry, 2024 - Elsevier
In order to find effective α-glucosidase inhibitors, a series of thiazolidine-2, 4-dione
derivatives (C1∼ 36) were synthesized and evaluated for α-glucosidase inhibitory activity …

Design, synthesis, biological evaluation, and docking study of new triazole-phenylacetamide derivatives as α-glucosidase inhibitors

S Luo, W Yang, Y Huang, Z Peng, G Wang - Bioorganic Chemistry, 2023 - Elsevier
To discover potent α-glucosidase inhibitors, a class of novel triazole-phenylacetamide
derivatives (5a-5p) were designed, prepared, and tested for their α-glucosidase inhibitory …

[HTML][HTML] Isatin-based ibuprofen and mefenamic acid Schiff base derivatives as dual inhibitors against urease and α–glucosidase: In vitro, in silico and cytotoxicity …

S Daud, M Saadullah, M Fakhar-e-Alam… - Journal of Saudi …, 2024 - Elsevier
Abstract α-Glucosidase and urease inhibitors have emerged as crucial for develo**
therapeutic drugs targeting diabetes and gastrointestinal disorders. This study reports on …

Computational exploration of phenolic compounds from endophytic fungi as α-glucosidase inhibitors for diabetes management

SA Kannakazhi Kantari, S Kanchi, B Patnaik… - ACS …, 2024 - ACS Publications
Diabetes has become a global epidemic, affecting even the younger people on an alarming
scale. Inhibiting intestinal α-glucosidase is one of the key approaches to managing type 2 …

Recent Progress on Natural α-glucosidase Inhibitors Derived from the Plants and Microorganisms

C Deng, N Zhang, H Lin, W Lu, F Ding… - Current Medicinal …, 2025 - ingentaconnect.com
α-Glucosidase inhibitors (AGIs) showcase versatile biochemical activities with respect to
antidiabetic, anticancerous, antiobese and antiviral effects. They have drawn a great deal of …

In-vitro, in-silico studies on the proposed penasulfate a and its derivatives as dual inhibitors of α-glucosidases and human cancer cells

C Deng, F Ding, C Zhao, N Zhang, H Lin, W Lu… - Journal of Molecular …, 2024 - Elsevier
Abstract α-Glucosidase inhibitors have been receiving significant attention from the scientific
community in recent years due to their potential in treating a variety of diseases, including …

Antimicrobial and enzymatic potential of Pterocarpus erinaceus Poir. endophytes used in Benin (West Africa)

S Aliou, B Fanou, JR Klotoé, E Agbodjento… - Bulletin of the National …, 2024 - Springer
Abstract Background Pterocarpus erinaceus Poir. is a plant widely used in traditional
medicine in Benin, treating various diseases such as diabetes, ulcers, parasitic infections …

[HTML][HTML] Global Phenolic Composition and Antioxidant Capacity of Extracts from the Endophytic Fungi Cophinforma mamane with Potential Use in Food Systems: The …

RS Gurgel, DIM Pereira, B Martins, LS Falcão… - Applied Sciences, 2024 - mdpi.com
Endophytic fungi are promising producers of phenolic compounds; however, the process of
extracting these molecules from the culture medium is a crucial step for obtaining these …

Novel approach to treat methicillin-resistant Staphylococcus aureus using endophyte-derived natural compounds

V Gunasekaran, P Sathishkumar - Natural Product Research, 2024 - Taylor & Francis
Green lab, department of Prosthodontics, saveetha dental college and hospital, sIMats,
saveetha university, chennai, India dear editor, Antimicrobial resistance in Staphylococcus …

Diversity and biological Potential of endophytes of Pterocarpus erinaceus used in Benin (West Africa): A Step Towards Conservation and New Pharmacological …

S Aliou, B Fanou, JR KLOTOE, E Agbodjento… - 2024 - researchsquare.com
Background Pterocarpus erinaceus is a plant widely used in traditional medicine in Benin,
treating various diseases such as diabetes, ulcers, parasitic infections, hypertension, and …