International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos, EH Ohlstein - Pharmacological reviews, 2017 - Elsevier
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms

C Szabo, C Ransy, K Módis… - British journal of …, 2014 - Wiley Online Library
Until recently, hydrogen sulfide (H2S) was exclusively viewed a toxic gas and an
environmental hazard, with its toxicity primarily attributed to the inhibition of mitochondrial C …

Hydrogen sulfide (H 2 S) releasing agents: chemistry and biological applications

Y Zhao, TD Biggs, M **an - Chemical communications, 2014 - pubs.rsc.org
Hydrogen sulfide (H2S) is a newly recognized signaling molecule with very potent
cytoprotective actions. The fields of H2S physiology and pharmacology have been rapidly …

[HTML][HTML] Emerging roles of cystathionine β-synthase in various forms of cancer

K Ascenção, C Szabo - Redox biology, 2022 - Elsevier
The expression of the reverse transsulfuration enzyme cystathionine-β-synthase (CBS) is
markedly increased in many forms of cancer, including colorectal, ovarian, lung, breast and …

Hydrogen sulfide in the mammalian cardiovascular system

YH Liu, M Lu, LF Hu, PTH Wong… - Antioxidants & redox …, 2012 - liebertpub.com
For more than a century, hydrogen sulfide (H2S) has been regarded as a toxic gas. This
review surveys the growing recognition of the role of H2S as an endogenous signaling …

Fluorescent probes for the detection of hydrogen sulfide in biological systems

W Xuan, C Sheng, Y Cao, W He… - Angewandte Chemie …, 2012 - Wiley Online Library
Although hydrogen sulfide (H2S) is known as a toxic gas with the unpleasant smell of rotten
eggs, this cannot change the fact that it exists in the human body and other biological …

H2S biosynthesis and catabolism: new insights from molecular studies

P Rose, PK Moore, YZ Zhu - Cellular and Molecular Life Sciences, 2017 - Springer
Hydrogen sulfide (H 2 S) has profound biological effects within living organisms and is now
increasingly being considered alongside other gaseous signalling molecules, such as nitric …

The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote …

I Andreadou, EK Iliodromitis, T Rassaf… - British journal of …, 2015 - Wiley Online Library
Ischaemic heart disease is one of the leading causes of morbidity and mortality worldwide.
The development of cardioprotective therapeutic agents remains a partly unmet need and a …

Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications

C Szabo - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Diabetes and its complications represent a major socioeconomic problem.
Recent Advances: Changes in the balance of hydrogen sulfide (H2S) play an important role …

A practical look at the chemistry and biology of hydrogen sulfide

KR Olson - Antioxidants & redox signaling, 2012 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) is garnering increasing interest as a
biologically relevant signaling molecule. The effects of H2S have now been observed in …