[HTML][HTML] Trends in pharmaceutical analysis and quality control by modern Raman spectroscopic techniques
The application of Raman spectroscopic methods in life science applications has entered a
new era due to advances in instrumentation, miniaturization and, most importantly …
new era due to advances in instrumentation, miniaturization and, most importantly …
A review of in-line and on-line measurement techniques to monitor industrial mixing processes
Mixing is a ubiquitous operation in process engineering. It is not only used for combining
materials, but also for promoting heat and mass transfer, increasing aeration, suspending …
materials, but also for promoting heat and mass transfer, increasing aeration, suspending …
On the particle formation of leucine in spray drying of inhalable microparticles
The particle formation of L-leucine, a dispersibility-enhancing amino acid used in the spray
drying of inhalable pharmaceutical aerosols, was extensively studied using three …
drying of inhalable pharmaceutical aerosols, was extensively studied using three …
A review of current techniques for the evaluation of powder mixing
Blending a mixture of powders to a homogeneous system is a crucial step in many
manufacturing processes. To achieve a high quality of the end product, powder mixtures …
manufacturing processes. To achieve a high quality of the end product, powder mixtures …
Development of a formulation platform for a spray-dried, inhalable tuberculosis vaccine candidate
Protection against primarily respiratory infectious diseases, such as tuberculosis (TB), can
likely be enhanced through mucosal immunization induced by direct delivery of vaccines to …
likely be enhanced through mucosal immunization induced by direct delivery of vaccines to …
Microparticle encapsulation of a tuberculosis subunit vaccine candidate containing a nanoemulsion adjuvant via spray drying
Spray drying is a technique that can be used to stabilize biopharmaceuticals, such as
vaccines, within dry particles. Compared to liquid pharmaceutical products, dry powder has …
vaccines, within dry particles. Compared to liquid pharmaceutical products, dry powder has …
[HTML][HTML] On the physical stability of leucine-containing spray-dried powders for respiratory drug delivery
Carrier-free spray-dried dispersions for pulmonary delivery, for which the demand is
growing, frequently require the incorporation of dispersibility-enhancing excipients into the …
growing, frequently require the incorporation of dispersibility-enhancing excipients into the …
Particle surface roughness improves colloidal stability of pressurized pharmaceutical suspensions
Purpose The effects of particle size and particle surface roughness on the colloidal stability
of pressurized pharmaceutical suspensions were investigated using monodisperse spray …
of pressurized pharmaceutical suspensions were investigated using monodisperse spray …
Inhalable microparticle platform based on a novel shell-forming lipid excipient and its feasibility for respirable delivery of biologics
Administration of biologics such as proteins, vaccines, and phages via the respiratory route
is becoming increasingly popular. Inhalable powder formulations for the successful delivery …
is becoming increasingly popular. Inhalable powder formulations for the successful delivery …
Leucine enhances the dispersibility of trehalose-containing spray-dried powders on exposure to a high-humidity environment
This study investigates the ability of various shell-forming excipients to preserve the
dispersibility of dry powder dosage forms, eg, nasally administered vaccines, upon exposure …
dispersibility of dry powder dosage forms, eg, nasally administered vaccines, upon exposure …