Seeking heterocyclic scaffolds as antivirals against dengue virus

S De, B Aamna, R Sahu, S Parida, SK Behera… - European Journal of …, 2022 - Elsevier
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …

Medicinal significance of benzothiazole scaffold: an insight view

PC Sharma, A Sinhmar, A Sharma… - Journal of enzyme …, 2013 - Taylor & Francis
Heterocycles bearing nitrogen, sulphur and thiazole moieties constitute the core structure of
a number of biologically interesting compounds. Benzothiazole, a group of xenobiotic …

A century-old one-pot multicomponent Biginelli reaction products still finds a niche in drug discoveries: Synthesis, mechanistic studies and diverse biological activities …

S Faizan, TF Roohi, RM Raju, Y Sivamani… - Journal of Molecular …, 2023 - Elsevier
One of the largest classes of organic molecules are dihydropyrimidines and its derivatives.
They are widely used in a variety of pharmacological and industrial applications. Their …

Synthesis, characterization, and DFT study of the s-triazine analogues of medicinal interest incorporated with five-and six-membered bioactive heterocyclic scaffolds

SZ Hashmi, J Dwivedi, D Kishore… - Journal of Molecular …, 2023 - Elsevier
The present paper reports the synthesis, NMR study, and detailed computational
investigation of various novel s-triazine analogues 9–12 of medicinal interest embellished …

Fe 3 O 4@ PEG-SO 3 H rod-like morphology along with the spherical nanoparticles: novel green nanocomposite design, preparation, characterization and catalytic …

A Maleki, P Zand, Z Mohseni - RSC Advances, 2016 - pubs.rsc.org
The design and preparation of polyethylene glycol sulfonic acid surface coated magnetic
nanoparticles (Fe3O4@ PEG-SO3H) is described. The morphology of the prepared …

Bi (III)-Catalyzed Michael Addition of Tautomerizable Heterocycles with α, β-Unsaturated Carbonyl Compounds: Regioselective Construction of C–N Bonds

S Maity, A Roy, S Duari, S Biswas… - The Journal of …, 2024 - ACS Publications
A Bi (III)-catalyzed synthetic strategy for regioselective construction of C–N bonds via a
simple Michael addition reaction is reported. A wide range of tautomerizable heterocycles …

Synthesis and antitumor activity of some nitrogen heterocycles bearing pyrimidine moiety

MH Ahmed, MA El‐Hashash… - Journal of …, 2020 - Wiley Online Library
Synthesis of novel pyrimidine derivatives 4‐16 was accomplished by heterocyclization of
polarized system, for example, Chalcone. Claisen‐Schmidt condensation of 2‐acetyl …

Cocrystals of 5-fluorouracil

A Delori, MD Eddleston, W Jones - CrystEngComm, 2013 - pubs.rsc.org
Cocrystals of 5-fluorouracil - CrystEngComm (RSC Publishing) DOI:10.1039/C2CE26147B
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/C2CE26147B …

Traditional, one-pot three-component synthesis and anti-bacterial evaluations of some new pyrimidine derivatives

SO Mamand, DA Abdul, MM Ayoob, AJ Hussein… - Inorganic Chemistry …, 2024 - Elsevier
In this study, a novel series of pyrimidine compounds featuring azo linkages was
synthesized via a sequence of stepwise and one-pot three-component reactions. The …

Anti-inflammatory effect of natural heterocycle glucoside vicine obtained from Vicia faba L. its aglucone (divicine) their effect on some oxidative stress biomarkers in …

MA Hussein - Free Radicals and Antioxidants, 2012 - Elsevier
Background: Inflammation is typically characterized by increased permeability of endothelial
tissue resulting in oedema. Much of pyrimidine derivatives have been highly useful for …