Angiogenesis and osteogenesis are coupled. However, the cellular and molecular
regulation of these processes remains to be further investigated. Both tissues have recently …

Besides the classical ones (support/protection, hematopoiesis, storage for calcium, and
phosphate) multiple roles emerged for bone tissue, definitively making it an organ …

Aim To clarify the role of mediators of ectopic mineralization as biomarkers for arterial
calcifications. Methods MEDLINE and Embase were searched for relevant literature, until …

The dissociation of bone formation and resorption is an important physiological process
during spaceflight. It also occurs during local skeletal unloading or immobilization, such as …

Background Emerging evidence demonstrates that bone is an endocrine organ capable of
influencing multiple physiological and pathological processes through the secretion of …

The phrase “skin as a mirror of internal medicine,” which means that the skin reflects many of
the diseases of the internal organs, is a well-known notion. Despite the phenotypic …

Hypoxia can lead to programmed osteoblast death. Prevention of osteoblast apoptosis
caused by hypoxia is of great significance in the study of the occurrence and development of …

Alzheimer's disease (AD) is a neurodegenerative disease that involves multiple systems in
the body. Numerous recent studies have revealed bidirectional crosstalk between the brain …

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD).
However, its pathogenesis remains unclear, and effective prevention and treatment …

Inter-organ communication through hormones, cytokines and extracellular vesicles (EVs)
has emerged to contribute to the physiological states and pathological processes of the …