Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology

AB Theberge, F Courtois, Y Schaerli… - Angewandte Chemie …, 2010 - Wiley Online Library
Microdroplets in microfluidics offer a great number of opportunities in chemical and
biological research. They provide a compartment in which species or reactions can be …

Micropumps, microvalves, and micromixers within PCR microfluidic chips: Advances and trends

C Zhang, D **ng, Y Li - Biotechnology advances, 2007 - Elsevier
This review surveys the advances of microvalves, micropumps, and micromixers within PCR
microfluidic chips over the past ten years. First, the types of microvalves in PCR chips are …

Droplet-based assay system

BW Colston, BJ Hindson, KD Ness… - US Patent …, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
42311957&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Droplet generation for droplet-based assays

KD Ness, CF Kelly, DA Masquelier - US Patent 9,500,664, 2016 - Google Patents
Many biomedical applications rely on high-throughput assays of samples combined with
reagents. For example, in research and clinical applications, high-throughput genetic tests …

High-throughput quantitative polymerase chain reaction in picoliter droplets

MM Kiss, L Ortoleva-Donnelly, NR Beer… - Analytical …, 2008 - ACS Publications
Limiting dilution PCR has become an increasingly useful technique for the detection and
quantification of rare species in a population, but the limit of detection and accuracy of …

Miniaturization through lab-on-a-chip: Utopia or reality for routine laboratories? A review

Á Ríos, M Zougagh, M Avila - Analytica chimica acta, 2012 - Elsevier
Micro total analysis (μTAS), also called “lab-on-a-chip (LOC)” technology, promises
solutions for high throughput and highly specific analysis for chemistry, biology and …

Microfluidic DNA amplification—A review

Y Zhang, P Ozdemir - Analytica chimica acta, 2009 - Elsevier
The application of microfluidic devices for DNA amplification has recently been extensively
studied. Here, we review the important development of microfluidic polymerase chain …

Method of mixing fluids by coalescence of multiple emulsions

BJ Hindson, BW Colston Jr, KD Ness… - US Patent …, 2015 - Google Patents
US9194861B2 - Method of mixing fluids by coalescence of multiple emulsions - Google Patents
US9194861B2 - Method of mixing fluids by coalescence of multiple emulsions - Google Patents …

System for forming an array of emulsions

KD Ness, BJ Hindson, BW Colston Jr… - US Patent …, 2015 - Google Patents
First worldwide family litigation filed litigation https://patents. darts-ip. com/? family=
42311957&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Micro total analysis systems: latest achievements

J West, M Becker, S Tombrink, A Manz - Analytical chemistry, 2008 - ACS Publications
The field of micro total analysis systems (μTAS), or “lab on a chip”, has continued to gain
maturity. The importance of μTAS is reflected in both the growing number and the improved …