Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences

F Pazan, M Wehling - European geriatric medicine, 2021 - Springer
Background The number of older adults has been constantly growing around the globe.
Consequently, multimorbidity and related polypharmacy have become an increasing …

Facing up to the global challenges of ageing

L Partridge, J Deelen, PE Slagboom - Nature, 2018 - nature.com
Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

An update on the clinical consequences of polypharmacy in older adults: a narrative review

JW Wastesson, L Morin, ECK Tan… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

[HTML][HTML] Adverse outcomes of polypharmacy in older people: systematic review of reviews

LE Davies, G Spiers, A Kingston, A Todd… - Journal of the American …, 2020 - Elsevier
Objective Polypharmacy is widespread among older people, but the adverse outcomes
associated with it are unclear. We aim to synthesize current evidence on the adverse health …

The C Factor: Cognitive dysfunction as a transdiagnostic dimension in psychopathology

A Abramovitch, T Short, A Schweiger - Clinical Psychology Review, 2021 - Elsevier
Research into cognitive functions across psychological disorders suggests that cognitive
deficiencies may be present across multiple disorders, potentially pointing to a …

An overview of prevalence, determinants and health outcomes of polypharmacy

M Khezrian, CJ McNeil, AD Murray… - … advances in drug …, 2020 - journals.sagepub.com
A high rate of polypharmacy is, in part, a consequence of the increasing proportion of
multimorbidity in the ageing population worldwide. Our understanding of the potential harm …

The epidemiology of polypharmacy in older adults: register-based prospective cohort study

L Morin, K Johnell, ML Laroche, J Fastbom… - Clinical …, 2018 - Taylor & Francis
Objective Polypharmacy is the concomitant use of several drugs by a single person, and it
increases the risk of adverse drug-related events in older adults. Little is known about the …

The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta‐analysis

AT Page, RM Clifford, K Potter… - British journal of …, 2016 - Wiley Online Library
Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …

[HTML][HTML] Adverse drug reactions, multimorbidity and polypharmacy: a prospective analysis of 1 month of medical admissions

R Osanlou, L Walker, DA Hughes, G Burnside… - BMJ open, 2022 - bmjopen.bmj.com
Objective To ascertain the burden and associated cost of adverse drug reactions (ADRs),
polypharmacy and multimorbidity through a prospective analysis of all medical admissions …