Cell-free DNA-based liquid biopsies in neurology

H Gaitsch, RJM Franklin, DS Reich - Brain, 2023 - academic.oup.com
This article reviews recent developments in the application of cell-free DNA-based liquid
biopsies to neurological diseases. Over the past few decades, an explosion of interest in the …

Beyond blood: Advancing the frontiers of liquid biopsy in oncology and personalized medicine

Y Bao, D Zhang, H Guo, W Ma - Cancer Science, 2024 - Wiley Online Library
Liquid biopsy is emerging as a pivotal tool in precision oncology, offering a noninvasive and
comprehensive approach to cancer diagnostics and management. By harnessing biofluids …

The current landscape of glioblastoma biomarkers in body fluids

S Zanganeh, E Abbasgholinejad, M Doroudian… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is a highly aggressive brain cancer, and early detection and
accurate diagnosis are crucial for effective treatment. Traditional diagnostic methods have …

Adding value to liquid biopsy for brain tumors: The role of imaging

N Khalili, H Shooli, N Hosseini, A Fathi Kazerooni… - Cancers, 2023 - mdpi.com
Simple Summary Clinical management in neuro-oncology has shifted to an integrated
method that combines molecular profiles with histopathological and imaging data. Liquid …

Plasma PD-L1 as a biomarker in the clinical management of glioblastoma multiforme—a retrospective cohort study

AB Masood, S Batool, SN Bhatti, A Ali, M Valko… - Frontiers in …, 2023 - frontiersin.org
Background and objectives Glioblastoma multiforme (GBM) is the most aggressive,
malignant, and therapy-resistant tumor of the brain. Blockade therapy targeting the …

Advances in nano-based materials for glioblastoma multiforme diagnosis: A mini-review

LA Gusmão, FS Matsuo, HFG Barbosa… - Frontiers in …, 2022 - frontiersin.org
The development of nano-based materials for diagnosis enables a more precise prognosis
and results. Inorganic, organic, or hybrid nanoparticles using nanomaterials, such as …

[HTML][HTML] A standardised methodology for the extraction and quantification of cell-free DNA in cerebrospinal fluid and application to evaluation of Alzheimer's disease …

P Takousis, AS Devonshire, N Redshaw… - New …, 2022 - Elsevier
Cerebrospinal fluid (CSF) is a source of diagnostic biomarkers for a range of neurological
conditions. Cell-free DNA (cfDNA) is detected in CSF and differences in the concentration of …

[HTML][HTML] Cell-free DNA end characteristics enable accurate and sensitive cancer diagnosis

J Ju, X Zhao, Y An, M Yang, Z Zhang, X Liu, D Hu… - Cell Reports …, 2024 - cell.com
The fragmentation patterns of cell-free DNA (cfDNA) in plasma can potentially be utilized as
diagnostic biomarkers in liquid biopsy. However, our knowledge of this biological process …

Immunohistochemistry detection of histone H3 K27M mutation in human glioma tissue

RS Tarapore, S Arain, E Blaine, A Hsiung… - Applied …, 2024 - journals.lww.com
The presence of the histone 3 (H3) K27M mutation in diffuse midline glioma has implications
for diagnosis, prognosis, and treatment, making rapid and accurate H3 K27M …

Ginsenosides as Promising Therapeutic Agents for Glioma: Mechanisms of Action and Future Perspectives

A Moftakhar, S Najafi, SE Khoshnam… - Current Chemical …, 2024 - benthamdirect.com
Brain cancers, particularly gliomas, are a significant cause of mortality worldwide. Gliomas
are primary tumors of the central nervous system (CNS) and are characterized by diverse …